Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16662475 | 0.81 | RORC (0.65) | RORC | |
| SCHEMBL16632692 | 0.81 | RORC (0.70) | RORC | |
| SCHEMBL16641814 | 0.78 | RORC (0.64) | RORC | |
| SCHEMBL16651451 | 0.78 | RORC (1.00) | RORC | |
| SCHEMBL19064360 | 0.76 | RORC (0.85) | RORC | |
| SCHEMBL16651289 | 0.76 | RORC (1.00) | RORC | |
| SCHEMBL16651799 | 0.75 | RORC (1.00) | RORC | |
| SCHEMBL19064227 | 0.75 | RORC (0.87) | RORC | |
| SCHEMBL16650875 | 0.75 | RORC (0.85) | RORC | |
| SCHEMBL16662487 | 0.74 | RORC (0.83) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057422-B1 | QUINOLINYL MODULATORS OF ROR(GAMMA)T | JANSSEN PHARMACEUTICA NV (BE) | 2019-05-15 | — | — | EP | disclosed |