⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23430621 | 0.80 | — | — | |
| SCHEMBL2394214 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL26644510 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL21722639 | 0.78 | — | — | |
| SCHEMBL30262653 | 0.76 | GBA1 (0.34) | — | |
| SCHEMBL19120997 | 0.75 | MAPK1 (0.34) | — | |
| SCHEMBL24091631 | 0.73 | — | — | |
| SCHEMBL19369241 | 0.73 | — | — | |
| SCHEMBL13543024 | 0.71 | HTR6 (0.34) | — | |
| SCHEMBL12029112 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190127375-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2019-05-02 | — | — | US | disclosed |