Teroxirone

Teroxirone

SCHEMBL2097151

O=c1n(C[C@@H]2CO2)c(=O)n(C[C@@H]2CO2)c(=O)n1C[C@@H]1CO1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 1.00
HBB P68871 1/20 1.00
SMN1; SMN2 Q16637 1/20 1.00
DHFR P00374 1/20 0.48
MAPT P10636 1/20 0.39
ALDH1A1 P00352 2/20 0.35
TSHR P16473 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
CDK4 P11802 1/20 0.33
CCND1 P24385 1/20 0.33
CCND2 P30279 1/20 0.33
CCND3 P30281 1/20 0.33
KDM4E B2RXH2 1/20 0.32
CYP3A4 P08684 1/20 0.31
MAPK14 Q16539 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Teroxirone SCHEMBL2097375 1.00 TP53 (1.00) TP53HBBSMN1; SMN2DHFRMAPT
Teroxirone SCHEMBL4452999 1.00 TP53 (1.00) TP53HBBSMN1; SMN2DHFRMAPT
Teroxirone SCHEMBL4461477 1.00 TP53 (1.00) TP53HBBSMN1; SMN2DHFRMAPT
Teroxirone SCHEMBL4932 1.00 TP53 (1.00) TP53HBBSMN1; SMN2DHFRMAPT
Teroxirone SCHEMBL4472568 1.00 TP53 (1.00) TP53HBBSMN1; SMN2DHFRMAPT
Teroxirone SCHEMBL4470513 1.00 TP53 (1.00) TP53HBBSMN1; SMN2DHFRMAPT
SCHEMBL10963410 0.93 TP53 (0.86) TP53HBBSMN1; SMN2DHFRMAPT
SCHEMBL17804388 0.89 TP53 (0.78) TP53HBBSMN1; SMN2DHFRMAPT
Teroxirone SCHEMBL10993252 0.89 TP53 (0.78) TP53HBBSMN1; SMN2DHFRMAPT
SCHEMBL1715098 0.89 TP53 (0.78) TP53HBBSMN1; SMN2DHFRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9567511-B2 Crosslinking resin for sand consolidation operations HALLIBURTON ENERGY SERVICES, INC. (US) 2017-02-14 US claimed
US-20160362599-A1 CROSSLINKING RESIN FOR SAND CONSOLIDATION OPERATIONS HALIBURTON ENERGY SERVICES, INC. (US) 2016-12-15 US claimed
WO-2016080974-A1 CROSSLINKING RESIN FOR SAND CONSOLIDATION OPERATIONS HALLIBURTON ENERGY SERVICES, INC. (US) 2016-05-26 WO claimed
WO-2011106545-A1 POLYIMIDAZOLES FOR USE AS BILE ACID SEQUESTRANTS RELYPSA, INC. (US) 2011-09-01 WO claimed
US-20180187066-A1 DELAYED REACTION TREATMENT ADDITIVE HALLIBURTON ENERGY SERVICES, INC. 2018-07-05 US disclosed
US-9567511-B2 Crosslinking resin for sand consolidation operations HALLIBURTON ENERGY SERVICES, INC. (US) 2017-02-14 US disclosed
WO-2017019066-A1 DELAYED REACTION TREATMENT ADDITIVE HALLIBURTON ENERGY SERVICES, INC. (US) 2017-02-02 WO disclosed
US-20160362599-A1 CROSSLINKING RESIN FOR SAND CONSOLIDATION OPERATIONS HALIBURTON ENERGY SERVICES, INC. (US) 2016-12-15 US disclosed
WO-2016080974-A1 CROSSLINKING RESIN FOR SAND CONSOLIDATION OPERATIONS HALLIBURTON ENERGY SERVICES, INC. (US) 2016-05-26 WO disclosed
US-8163799-B2 Amido-amine polymer compositions GENZYME CORPORATION (US) 2012-04-24 US disclosed
WO-2011106545-A1 POLYIMIDAZOLES FOR USE AS BILE ACID SEQUESTRANTS RELYPSA, INC. (US) 2011-09-01 WO disclosed