Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 1.00 |
| ▸ | HBB | P68871 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | DHFR | P00374 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CCND2 | P30279 | 1/20 | 0.33 |
| ▸ | CCND3 | P30281 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Teroxirone SCHEMBL4452999 | 1.00 | TP53 (1.00) | TP53HBBSMN1; SMN2DHFRMAPT | |
| Teroxirone SCHEMBL2097151 | 1.00 | TP53 (1.00) | TP53HBBSMN1; SMN2DHFRMAPT | |
| Teroxirone SCHEMBL4461477 | 1.00 | TP53 (1.00) | TP53HBBSMN1; SMN2DHFRMAPT | |
| Teroxirone SCHEMBL4932 | 1.00 | TP53 (1.00) | TP53HBBSMN1; SMN2DHFRMAPT | |
| Teroxirone SCHEMBL4472568 | 1.00 | TP53 (1.00) | TP53HBBSMN1; SMN2DHFRMAPT | |
| Teroxirone SCHEMBL4470513 | 1.00 | TP53 (1.00) | TP53HBBSMN1; SMN2DHFRMAPT | |
| SCHEMBL10963410 | 0.93 | TP53 (0.86) | TP53HBBSMN1; SMN2DHFRMAPT | |
| SCHEMBL17804388 | 0.89 | TP53 (0.78) | TP53HBBSMN1; SMN2DHFRMAPT | |
| Teroxirone SCHEMBL10993252 | 0.89 | TP53 (0.78) | TP53HBBSMN1; SMN2DHFRMAPT | |
| SCHEMBL1715098 | 0.89 | TP53 (0.78) | TP53HBBSMN1; SMN2DHFRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106545-A1 | POLYIMIDAZOLES FOR USE AS BILE ACID SEQUESTRANTS | RELYPSA, INC. (US) | 2011-09-01 | — | — | WO | claimed |
| US-20140044671-A1 | AMINE CONDENSATION POLYMERS AS PHOSPHATE SEQUESTRANTS | GENZYME CORPORATION (US) | 2014-02-13 | — | — | US | disclosed |
| EP-1375498-B1 | Optically active epoxy compound | NISSAN CHEMICAL IND LTD (JP) | 2013-01-09 | — | — | EP | disclosed |
| US-8163799-B2 | Amido-amine polymer compositions | GENZYME CORPORATION (US) | 2012-04-24 | — | — | US | disclosed |
| WO-2011106545-A1 | POLYIMIDAZOLES FOR USE AS BILE ACID SEQUESTRANTS | RELYPSA, INC. (US) | 2011-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140044671-A1 | AMINE CONDENSATION POLYMERS AS PHOSPHATE SEQUESTRANTS | PHPT1, CEPT1, PNMT | TP53 2727/4885HBB 4466/4885SMN1; SMN2 2830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.