Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.73 |
| ▸ | MAPT | P10636 | 4/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11331749 | 0.94 | GAA (0.70) | GAAMAPTALDH1A1PPARGAPP | |
| SCHEMBL11327473 | 0.92 | GAA (0.68) | GAAMAPTALDH1A1PPARGAPP | |
| SCHEMBL11335452 | 0.92 | GAA (0.68) | GAAMAPTALDH1A1PPARGAPP | |
| SCHEMBL11333048 | 0.92 | GAA (0.68) | GAAMAPTALDH1A1PPARGAPP | |
| SCHEMBL3631474 | 0.92 | GAA (0.68) | GAAMAPTALDH1A1PPARGAPP | |
| SCHEMBL11225712 | 0.92 | GAA (0.68) | GAAMAPTALDH1A1PPARGAPP | |
| SCHEMBL7001977 | 0.92 | GAA (0.68) | GAAMAPTALDH1A1PPARGAPP | |
| SCHEMBL11338984 | 0.92 | GAA (0.68) | GAAMAPTALDH1A1PPARGAPP | |
| Cyclopropane SCHEMBL28852061 | 0.89 | GAA (0.63) | GAAMAPTALDH1A1PPARGAPP | |
| SCHEMBL613598 | 0.88 | GAA (0.79) | GAAMAPTALDH1A1PPARGAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104370759-B | A kind of preparation method of deuterated dimethyl Ractopamine hydrochloride | SHANGHAI INSTITUTE OF TECHNOLOGY (CN) | 2016-04-27 | — | — | CN | claimed |
| CN-104370759-A | Preparation method of deuterated dimethyl ractopamine | SHANGHAI INST TECHNOLOGY | 2015-02-25 | — | — | CN | claimed |
| CN-115448909-B | N-carbazolyl-1H-pyrrole-2-carboxamide and application thereof as ligand in copper-catalyzed C-N coupling reaction | 中山大学 | 2023-10-27 | — | — | CN | disclosed |
| EP-3812040-B1 | COMPLEXES | JOHNSON MATTHEY PLC (GB) | 2023-01-11 | — | — | EP | disclosed |
| CN-115448909-A | N-carbazolyl-1H-pyrrole-2-formamide and application thereof as ligand in copper-catalyzed C-N coupling reaction | 中山大学 | 2022-12-09 | — | — | CN | disclosed |
| CN-110201721-B | Complex compounds | 庄信万丰股份有限公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-109456205-B | N-arylation method in aqueous phase system by using substituted quinoline or isoquinoline hydrazide pyridine-N-oxide as ligand | 石河子大学 | 2021-09-21 | — | — | CN | disclosed |
| EP-3812040-A1 | COMPLEXES | Johnson Matthey Public Limited Company (GB) | 2021-04-28 | — | — | EP | disclosed |
| EP-3154689-B1 | COMPLEXES | JOHNSON MATTHEY PLC (GB) | 2021-01-27 | — | — | EP | disclosed |
| CN-106661071-B | Complex compounds | 庄信万丰股份有限公司 | 2020-06-09 | — | — | CN | disclosed |
| CN-109456205-A | Using substd quinolines or isoquinolin hydrazides pyridine-N-oxides as the N- arylation method in the aqueous phase system of ligand | 石河子大学 | 2019-03-12 | — | — | CN | disclosed |
| US-20070123707-A1 | Nitrogen-containing monodentate phosphines and their use in catalysis | DEGUSSA AG (DE) | 2007-05-31 | — | — | US | disclosed |
| WO-2006084246-A2 | AROMATIC AMIDES AND UREAS AND THEIR USES AS SWEET AND/OR UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | SENOMYX, INC. (US) | 2006-08-10 | — | — | WO | disclosed |
| EP-1659881-A2 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | Senomyx Inc. (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005041684-A2 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | SENOMYX INC. (US) | 2005-05-12 | — | — | WO | disclosed |
| EP-0612724-B1 | Substituted benzenesulfonylureas and -thioureas, process for their preparation and their use as pharmaceuticals | HOECHST AG (DE) | 1996-12-27 | — | — | EP | disclosed |
| EP-0612724-A1 | Substituted benzenesulfonylureas and -thioureas, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-08-31 | — | — | EP | disclosed |
| EP-0002721-B1 | PROCESS FOR PREPARING HYDRAZINES | BAYER AG (DE) | 1981-09-02 | — | — | EP | disclosed |
| EP-0002721-A2 | Process for preparing hydrazines | BAYER AG (DE) | 1979-07-11 | — | — | EP | disclosed |
| US-4076849-A | AROMATIC SECONDARY AMINES | CANADA PACKERS LIMITED (CA) | 1978-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123707-A1 | Nitrogen-containing monodentate phosphines and their use in catalysis | HDHD5, PNP, PHOSPHO1 | GAA 3420/4885MAPT 3766/4885ALDH1A1 3129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.