Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.64 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.64 |
| ▸ | AXL | P30530 | 1/20 | 0.64 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.62 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.62 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.62 |
| ▸ | KMO | O15229 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29398069 | 1.00 | CYP2A6 (0.68) | CYP2A6ALDH1A1CYP1A2CYP3A4MKNK1 | |
| SCHEMBL8385276 | 1.00 | CYP2A6 (0.68) | CYP2A6ALDH1A1CYP1A2CYP3A4MKNK1 | |
| SCHEMBL31663576 | 1.00 | CYP2A6 (0.68) | CYP2A6ALDH1A1CYP1A2CYP3A4MKNK1 | |
| SCHEMBL18134279 | 0.98 | CYP19A1 (0.66) | CYP2A6ALDH1A1CYP1A2CYP3A4MKNK1 | |
| SCHEMBL21396881 | 0.98 | CYP19A1 (0.66) | CYP2A6ALDH1A1CYP1A2CYP3A4MKNK1 | |
| SCHEMBL24492828 | 0.98 | CYP19A1 (0.66) | CYP2A6ALDH1A1CYP1A2CYP3A4MKNK1 | |
| SCHEMBL17189941 | 0.98 | CYP19A1 (0.66) | CYP2A6ALDH1A1CYP1A2CYP3A4MKNK1 | |
| SCHEMBL15982379 | 0.98 | CYP19A1 (0.66) | CYP2A6ALDH1A1CYP1A2CYP3A4MKNK1 | |
| SCHEMBL18650174 | 0.98 | CYP19A1 (0.66) | CYP2A6ALDH1A1CYP1A2CYP3A4MKNK1 | |
| SCHEMBL24493204 | 0.98 | CYP19A1 (0.66) | CYP2A6ALDH1A1CYP1A2CYP3A4MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11236093-B2 | Adenine derivatives as protein kinase inhibitors | B.C.I. PHARMA (BE) | 2022-02-01 | — | — | US | disclosed |
| US-20190127379-A1 | ADENINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | B.C.I. PHARMA (BE) | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11236093-B2 | Adenine derivatives as protein kinase inhibitors | ADK, TNNI3K, TNK2 | CYP2A6 3933/4885ALDH1A1 3196/4885CYP1A2 3450/4885 |
| US-20190127379-A1 | ADENINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | ADK, TNNI3K, TNK2 | CYP2A6 3933/4885ALDH1A1 3196/4885CYP1A2 3450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.