SCHEMBL20973241

SCHEMBL20973241

CC1(C)CC(=O)N(Cc2cc3nccc(Cl)c3s2)C(=O)C1

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
USP7 Q93009 18/20 0.46
KCNH2 Q12809 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20973748 0.86 USP7 (0.53) USP7KCNH2
SCHEMBL20973469 0.86 USP7 (0.42) USP7KCNH2
SCHEMBL20974064 0.84 USP7 (0.49) USP7KCNH2
SCHEMBL25283308 0.81 USP7 (0.54) USP7KCNH2
SCHEMBL20974023 0.81 USP7 (0.40) USP7KCNH2
SCHEMBL20973603 0.81 USP7 (0.40) USP7KCNH2
SCHEMBL20973368 0.81 USP7 (0.42) USP7KCNH2
SCHEMBL23910774 0.81 USP7 (0.44) USP7KCNH2
SCHEMBL20973433 0.80 USP7 (0.44) USP7KCNH2
SCHEMBL20973854 0.80 ELANE (0.47) USP7KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10722514-B2 Ubiquitin-specific-processing protease 7 (USP7) modulators and uses thereof RAPT THERAPEUTICS, INC. (US) 2020-07-28 US disclosed
US-20190142834-A1 UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF RAPT THERAPEUTICS, INC. 2019-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190142834-A1 UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF USP7, SENP7, USP8 USP7 1/4885KCNH2 4865/4885
US-10722514-B2 Ubiquitin-specific-processing protease 7 (USP7) modulators and uses thereof USP7, SENP7, USP8 USP7 1/4885KCNH2 4865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.