SENP7 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL61076	0.52	5/20
SCHEMBL61077	0.52	5/20
SCHEMBL66528	0.52	5/20
Benoxaprofen (SCHEMBL24413)	0.58	4/20
Benoxaprofen (SCHEMBL24414)	0.58	4/20
SCHEMBL95847	0.41	4/20
SCHEMBL95401	0.57	3/20
SCHEMBL58807	0.57	3/20
SCHEMBL95851	0.56	3/20
SCHEMBL12261	0.54	3/20
Chlorzoxazone (SCHEMBL35177)	0.54	3/20
SCHEMBL95850	0.54	3/20
SCHEMBL38212	0.53	3/20
SCHEMBL38213	0.53	3/20
SCHEMBL26386	0.48	3/20
SCHEMBL59246	0.47	3/20
SCHEMBL38871	0.47	3/20
SCHEMBL38872	0.47	3/20
SCHEMBL25796	0.42	3/20
SCHEMBL38214	0.36	3/20

Clinical trials — most relevant to SENP7 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Can We Achieve 'high-quality' Weight Loss Through Supplementation and Exercise? the TRIM MUSCLE Study	PHASE3	COMPLETED
Strategies to Reduce Organic Muscle Atrophy in the Intensive Care Unit	PHASE2/PHASE3	WITHDRAWN
Signal TrAnsduction Pathway Activity Analysis in OVarian cancER	PHASE2/PHASE3	RECRUITING
A Study of Hydroxychloroquine in Combination With Gemcitabine/Abraxane in Pancreatic Cancer	PHASE1/PHASE2	COMPLETED
Inhibition of SENP1 for the Suppression of OS Growth and Metastasis	nan	UNKNOWN
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis	nan	UNKNOWN
Evaluation of Prognostic Factors: From Breast Cancer to Bone Metastases	nan	UNKNOWN
Autophagy Bladder Cancer	nan	UNKNOWN
Circulating Markers for Ischemic Heart Disease	nan	RECRUITING
Circulating Markers That Underlie the Transition From Compensated Hypertrophy to Heart Failure	nan	RECRUITING
Apoptosis Markers in Aggressive Periodontitis	nan	COMPLETED
Clinical Manifestations and Biomarkers in Amyotrophic Lateral Sclerosis Type 4 and Other Inherited Neurological Disorders of RNA Processing	nan	RECRUITING
Effect of Dietary Nitrate on Immobilization-induced Changes in Skeletal Muscle in Young Healthy Men	nan	RECRUITING
Genetic Mechanisms of Chronic Obstructive Pulmonary Disease (COPD)	nan	COMPLETED
Diagnostic Potential of UCHL1 in Acute Decompensated Heart Failure	nan	COMPLETED
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA	nan	RECRUITING
Genetic Variation in TRAF3IP2 (rs13190932)	nan	RECRUITING
Integrated Proteomic HPLC-ESI-MS Analysis of Salivary Peptides of Preterm Newborns: a Pilot Study	nan	COMPLETED
Identification of a New Blood Biomarker for the Diagnosis and Prognosis of Liposarcomas	nan	RECRUITING
Role of Serum ADAM 17 (A Disintegrin And Metalloprotease 17) and Caspase 3 in Patients With Chronic Kidney Disease	nan	NOT_YET_RECRUITING
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Expression and Clinical Significance of IGHD in Pancreatic Cancer	nan	UNKNOWN
Exosome-based Liquid Biopsies for Upper Gastrointestinal Cancers Diagnosis	nan	UNKNOWN
Hydroxychloroquin (HCQ) in chILD of Genetic Defect	nan	COMPLETED
Biomarkers in Tumor Samples From Younger Patients With Neuroblastoma	nan	COMPLETED
Long Term Prediction of MASH-related HCC Risk by Proteomics	nan	NOT_YET_RECRUITING
Genetic Testing in Young Adults With Cancer Study	nan	COMPLETED
Patient's Derived Organoids for Drug Screening in Glioblastoma	nan	NOT_YET_RECRUITING
Analysis of the Variation in Caspase-8 Availability and Cleavage in Oral Squamous Cell Carcinoma	nan	UNKNOWN
Amplification of Zinc Finger Protein 217 Gene in Multiple Myeloma	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a SENP7 binder may also engage these)

Protein	Name	Similarity
A7MBJ2	—	0.999	A7MBJ2 →
D3ZF42	—	0.995	D3ZF42 →
Q8BUH8	—	0.995	Q8BUH8 →
A0JM80	—	0.989	A0JM80 →
Q6GPJ8	—	0.988	Q6GPJ8 →
DCLRE1A	DNA cross-link repair 1A protein	0.988	landscape →
Q32MH5	—	0.988	Q32MH5 →
Q5QJC4	—	0.988	Q5QJC4 →
Q6ZV73	—	0.988	Q6ZV73 →
P56716	—	0.988	P56716 →
Q6DFV7	—	0.988	Q6DFV7 →
Q5T5J6	—	0.988	Q5T5J6 →
Q9CUU3	—	0.987	Q9CUU3 →
P62292	—	0.987	P62292 →
Q5ZI58	—	0.987	Q5ZI58 →
Q6P7W0	—	0.987	Q6P7W0 →
Q5W0B1	—	0.987	Q5W0B1 →
P62291	—	0.987	P62291 →
Q6GNV6	—	0.987	Q6GNV6 →
Q5RD97	—	0.987	Q5RD97 →
Q8L7S0	—	0.987	Q8L7S0 →
Q80Y19	—	0.987	Q80Y19 →
Q9BX26	—	0.986	Q9BX26 →
Q9UHC1	—	0.986	Q9UHC1 →
P62287	—	0.986	P62287 →
Q99708	—	0.986	Q99708 →
Q5FBB7	—	0.986	Q5FBB7 →
Q6P4F7	—	0.986	Q6P4F7 →
Q3V089	—	0.986	Q3V089 →
Q5VYS8	—	0.985	Q5VYS8 →