Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 12/20 | 0.56 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RAF1 | P04049 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20357201 | 0.88 | EPHX2 (0.62) | EPHX2RAF1FAAH | |
| SCHEMBL18615522 | 0.88 | EPHX2 (0.62) | EPHX2RAF1FAAH | |
| SCHEMBL20357297 | 0.86 | MEN1 (0.47) | EPHX2MEN1KMT2ARAF1KDM4E | |
| SCHEMBL18615448 | 0.86 | MEN1 (0.47) | EPHX2MEN1KMT2ARAF1KDM4E | |
| SCHEMBL20357351 | 0.86 | KDR (0.46) | EPHX2MEN1KMT2ARAF1KDM4E | |
| SCHEMBL18615495 | 0.86 | KDR (0.46) | EPHX2MEN1KMT2ARAF1KDM4E | |
| SCHEMBL20976430 | 0.83 | RAF1 (0.47) | EPHX2RAF1LMNABRAF | |
| SCHEMBL18615451 | 0.81 | MEN1 (0.69) | EPHX2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL20357355 | 0.81 | KDR (0.45) | MEN1KMT2ARAF1KDM4EALDH1A1 | |
| SCHEMBL18615652 | 0.81 | KDR (0.45) | MEN1KMT2ARAF1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10280145-B2 | Urea derivative and use therefor | TORAY INDUSTRIES, INC. (JP) | 2019-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10280145-B2 | Urea derivative and use therefor | UTS2R, DDR1, WEE1 | EPHX2 4826/4885TEAD1 1567/4885MEN1 603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.