Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | POLA1 | P09884 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | ADA | P00813 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12149981 | 0.86 | KDM4E (0.46) | KDM4EHPGDPOLA1TAS1R3TAS1R1 | |
| SCHEMBL1378141 | 0.86 | KDM4E (0.60) | KDM4EHPGDPOLA1TAS1R3TAS1R1 | |
| SCHEMBL1378135 | 0.86 | KDM4E (0.60) | KDM4EHPGDPOLA1TAS1R3TAS1R1 | |
| SCHEMBL12758450 | 0.86 | HPGD (0.46) | KDM4EHPGDPOLA1ADORA2AADORA3 | |
| SCHEMBL17357693 | 0.86 | HPGD (0.46) | KDM4EHPGDPOLA1ADORA2AADORA3 | |
| SCHEMBL12281166 | 0.84 | ADORA3 (0.48) | HPGDADORA2AADORA3 | |
| SCHEMBL12194531 | 0.84 | ADORA3 (0.48) | HPGDADORA2AADORA3 | |
| SCHEMBL16023838 | 0.84 | ADORA3 (0.48) | HPGDADORA2AADORA3 | |
| SCHEMBL20977459 | 0.84 | ADORA3 (0.48) | HPGDADORA2AADORA3 | |
| SCHEMBL1375512 | 0.84 | ADORA3 (0.48) | HPGDADORA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2120566-B1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF VIRAL INFECTIONS | IDENIX PHARMACEUTICALS LLC (US) | 2019-05-08 | — | — | EP | disclosed |