Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 20/20 | 0.63 |
| ▸ | ESRRB | O95718 | 11/20 | 0.57 |
| ▸ | ESR1 | P03372 | 9/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | ESRRA | P11474 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20842143 | 0.81 | ESRRG (0.76) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL20842127 | 0.78 | ESRRG (0.98) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL20978454 | 0.77 | ESRRG (0.69) | ESRRGESRRBESR1KCNH2 | |
| SCHEMBL20842090 | 0.75 | ESRRG (0.53) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL20978547 | 0.73 | ESRRG (0.53) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL24505371 | 0.73 | ESRRG (0.70) | ESRRGESRRBESR1KCNH2 | |
| SCHEMBL20842049 | 0.73 | ESRRG (0.58) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL20842022 | 0.73 | ESRRG (1.00) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL20842122 | 0.72 | ESRRG (0.98) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL20842031 | 0.71 | ESRRG (0.98) | ESRRGESRRBESR1KCNH2ESRRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3480186-A1 | NOVEL ARYL ETHANE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | Kemimedi Co. Ltd (KR) | 2019-05-08 | — | — | EP | disclosed |