Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 20/20 | 0.53 |
| ▸ | ESRRB | O95718 | 13/20 | 0.53 |
| ▸ | ESR1 | P03372 | 10/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.52 |
| ▸ | ESRRA | P11474 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20978510 | 0.81 | ESRRG (0.68) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL20978471 | 0.81 | ESRRG (0.67) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL24505504 | 0.78 | ESRRG (0.51) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL20978409 | 0.73 | ESRRG (0.63) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL24354534 | 0.69 | ESRRG (0.68) | ESRRGESRRBESR1KCNH2 | |
| SCHEMBL20978467 | 0.69 | ESRRG (0.70) | ESRRGESRRBESR1KCNH2 | |
| SCHEMBL20842048 | 0.69 | ESRRG (0.67) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL20842009 | 0.68 | ESRRG (0.73) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL20978521 | 0.68 | ESRRG (0.58) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL24505344 | 0.68 | ESRRG (0.54) | ESRRGESRRBESR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3480186-A1 | NOVEL ARYL ETHANE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | Kemimedi Co. Ltd (KR) | 2019-05-08 | — | — | EP | disclosed |