Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 11/20 | 0.53 |
| ▸ | KDM2B | Q8NHM5 | 5/20 | 0.53 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.51 |
| ▸ | KDM5C | P41229 | 9/20 | 0.47 |
| ▸ | KDM3A | Q9Y4C1 | 6/20 | 0.47 |
| ▸ | KDM2A | Q9Y2K7 | 6/20 | 0.47 |
| ▸ | KDM6B | O15054 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.46 |
| ▸ | KDM5A | P29375 | 2/20 | 0.46 |
| ▸ | KDM4A | O75164 | 7/20 | 0.46 |
| ▸ | KDM4B | O94953 | 2/20 | 0.46 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20978704 | 0.79 | KDM4C (0.55) | KDM4CKDM2BJMJD6KDM5CKDM3A | |
| SCHEMBL20978798 | 0.76 | KDM4C (0.57) | KDM4CKDM2BJMJD6KDM5BKDM5A | |
| SCHEMBL20978714 | 0.75 | KDM4C (0.60) | KDM4CKDM2BJMJD6KDM5CKDM3A | |
| SCHEMBL20978803 | 0.75 | KDM4C (0.58) | KDM4CKDM2BJMJD6KDM5CKDM5B | |
| SCHEMBL20978914 | 0.75 | KDM4C (0.58) | KDM4CKDM2BJMJD6KDM5CKDM3A | |
| SCHEMBL20978795 | 0.74 | KDM4C (0.60) | KDM4CKDM2BJMJD6KDM5CKDM3A | |
| SCHEMBL29145054 | 0.74 | KDM4C (0.75) | KDM4CKDM2BJMJD6KDM5CKDM3A | |
| SCHEMBL20978916 | 0.74 | KDM4C (0.59) | KDM4CKDM2BJMJD6KDM5CKDM3A | |
| SCHEMBL20979006 | 0.72 | JMJD6 (0.54) | KDM4CKDM2BJMJD6KDM5CKDM3A | |
| SCHEMBL70700 | 0.72 | KDM4C (0.78) | KDM4CKDM2BJMJD6KDM5CKDM3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2019-05-08 | — | — | EP | disclosed |