Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 6/20 | 0.64 |
| ▸ | KDM4C | Q9H3R0 | 12/20 | 0.49 |
| ▸ | KDM5A | P29375 | 4/20 | 0.46 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.46 |
| ▸ | KDM5C | P41229 | 2/20 | 0.41 |
| ▸ | KDM4A | O75164 | 2/20 | 0.40 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.40 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.39 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20978805 | 0.87 | KDM5B (0.59) | KDM2BKDM4CKDM5AKDM5BKDM5C | |
| SCHEMBL20978721 | 0.86 | KDM4C (0.68) | KDM2BKDM4CKDM5AKDM5BKDM5C | |
| SCHEMBL20978804 | 0.80 | KDM2B (0.63) | KDM2BKDM4CKDM5AKDM5BKDM5C | |
| SCHEMBL20978815 | 0.79 | KDM4C (0.48) | KDM2BKDM4CKDM5AKDM5BKDM5C | |
| SCHEMBL20978718 | 0.79 | KDM4C (0.63) | KDM2BKDM4CKDM5AKDM5BKDM5C | |
| SCHEMBL16033966 | 0.78 | KDM2B (1.00) | KDM2BKDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL20978862 | 0.76 | KDM4C (0.68) | KDM2BKDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL20978859 | 0.75 | KDM2B (0.44) | KDM2BKDM4CKDM5AKDM5BKDM5C | |
| SCHEMBL16075659 | 0.75 | KDM2B (0.92) | KDM2BKDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL20979006 | 0.74 | JMJD6 (0.54) | KDM2BKDM4CKDM5AKDM5BKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2019-05-08 | — | — | EP | disclosed |