Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 13/20 | 0.63 |
| ▸ | KDM4A | O75164 | 3/20 | 0.63 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.45 |
| ▸ | KDM5A | P29375 | 3/20 | 0.45 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20978805 | 0.86 | KDM5B (0.59) | KDM4CKDM4AKDM5BKDM5AJMJD6 | |
| SCHEMBL20978862 | 0.81 | KDM4C (0.68) | KDM4CKDM4AKDM5BKDM5AKDM2B | |
| SCHEMBL20978783 | 0.79 | KDM2B (0.64) | KDM4CKDM4AKDM5BKDM5AJMJD6 | |
| SCHEMBL20978804 | 0.79 | KDM2B (0.63) | KDM4CKDM4AKDM5BKDM5AJMJD6 | |
| SCHEMBL16033374 | 0.78 | KDM4C (1.00) | KDM4CKDM4AKDM5BKDM5AKDM2B | |
| SCHEMBL20978815 | 0.75 | KDM4C (0.48) | KDM4CKDM4AKDM5BKDM5AKDM2B | |
| SCHEMBL20978720 | 0.73 | KDM4C (0.69) | KDM4CKDM4AKDM5BKDM5AKDM2B | |
| SCHEMBL20979006 | 0.73 | JMJD6 (0.54) | KDM4CKDM4AKDM5BKDM5AJMJD6 | |
| SCHEMBL20978807 | 0.73 | KDM5B (0.62) | KDM4CKDM4AKDM5BKDM5AJMJD6 | |
| SCHEMBL20978859 | 0.72 | KDM2B (0.44) | KDM4CKDM4AKDM5BKDM5AJMJD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2019-05-08 | — | — | EP | disclosed |