Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.62 |
| ▸ | KDM5A | P29375 | 3/20 | 0.62 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.43 |
| ▸ | KDM5C | P41229 | 5/20 | 0.43 |
| ▸ | KDM4A | O75164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4B | O94953 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.41 |
| ▸ | KDM3A | Q9Y4C1 | 3/20 | 0.41 |
| ▸ | KDM6B | O15054 | 2/20 | 0.41 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20978859 | 0.83 | KDM2B (0.44) | KDM5BKDM5AKDM2BJMJD6KDM4C | |
| SCHEMBL20978805 | 0.81 | KDM5B (0.59) | KDM5BKDM5AKDM2BJMJD6KDM4C | |
| SCHEMBL20978910 | 0.77 | KDM5A (0.60) | KDM5BKDM5AKDM2BJMJD6KDM4C | |
| SCHEMBL16034328 | 0.77 | KDM5A (1.00) | KDM5BKDM5AKDM2BKDM4CKDM4A | |
| SCHEMBL20978938 | 0.77 | KDM4C (0.67) | KDM5BKDM5AKDM2BKDM4CKDM5C | |
| SCHEMBL20978723 | 0.76 | KDM2B (0.38) | KDM5BKDM5AKDM2BJMJD6KDM4C | |
| SCHEMBL20979006 | 0.76 | JMJD6 (0.54) | KDM5BKDM5AKDM2BJMJD6KDM4C | |
| SCHEMBL20978804 | 0.75 | KDM2B (0.63) | KDM5BKDM5AKDM2BJMJD6KDM4C | |
| SCHEMBL20978722 | 0.75 | KDM4C (0.68) | KDM5BKDM5AKDM2BJMJD6KDM4C | |
| SCHEMBL20979022 | 0.74 | KDM4C (0.46) | KDM5BKDM5AKDM2BJMJD6KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2019-05-08 | — | — | EP | disclosed |