Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.68 |
| ▸ | KDM4A | O75164 | 5/20 | 0.68 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.68 |
| ▸ | KDM5A | P29375 | 8/20 | 0.46 |
| ▸ | KDM5B | Q9UGL1 | 7/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20978938 | 0.83 | KDM4C (0.67) | KDM4CKDM4AKDM2BKDM5AKDM5B | |
| SCHEMBL16033490 | 0.81 | KDM4C (1.00) | KDM4CKDM4AKDM2BKDM5AKDM5B | |
| SCHEMBL20978910 | 0.78 | KDM5A (0.60) | KDM4CKDM4AKDM2BKDM5AKDM5B | |
| SCHEMBL16035034 | 0.76 | KDM4C (1.00) | KDM4CKDM4AKDM2BKDM5AKDM5B | |
| SCHEMBL20978807 | 0.75 | KDM5B (0.62) | KDM4CKDM4AKDM2BKDM5AKDM5B | |
| SCHEMBL20978859 | 0.74 | KDM2B (0.44) | KDM4CKDM4AKDM2BKDM5AKDM5B | |
| SCHEMBL20978805 | 0.73 | KDM5B (0.59) | KDM4CKDM4AKDM2BKDM5AKDM5B | |
| SCHEMBL16095000 | 0.73 | KDM4C (0.66) | KDM4CKDM4AKDM2BKDM5AKDM5B | |
| SCHEMBL20978815 | 0.73 | KDM4C (0.48) | KDM4CKDM4AKDM2BKDM5AKDM5B | |
| SCHEMBL20978783 | 0.69 | KDM2B (0.64) | KDM4CKDM4AKDM2BKDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2019-05-08 | — | — | EP | disclosed |