Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.46 |
| ▸ | KDM5A | P29375 | 6/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 6/20 | 0.45 |
| ▸ | KDM2B | Q8NHM5 | 5/20 | 0.44 |
| ▸ | KDM4A | O75164 | 4/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16033691 | 0.82 | KDM5A (0.60) | KDM4CKDM5AKDM5BKDM2BKDM4A | |
| SCHEMBL16034020 | 0.80 | KDM5A (0.52) | KDM4CKDM5AKDM5BKDM2BKDM4A | |
| SCHEMBL16033745 | 0.76 | KDM5A (0.58) | KDM4CKDM5AKDM5BKDM2BKDM4A | |
| SCHEMBL16033896 | 0.74 | KDM2B (0.65) | KDM4CKDM5AKDM5BKDM2BKDM4A | |
| SCHEMBL16126212 | 0.74 | KDM5A (0.43) | KDM4CKDM5AKDM5BKDM2BKDM4A | |
| SCHEMBL16034584 | 0.73 | KDM5A (0.41) | KDM4CKDM5AKDM5BKDM2BKDM4A | |
| SCHEMBL16034468 | 0.73 | KDM2B (0.43) | KDM4CKDM5AKDM5BKDM2BKDM4A | |
| SCHEMBL16034388 | 0.70 | KDM2B (0.60) | KDM4CKDM5AKDM5BKDM2BKDM4A | |
| SCHEMBL16033539 | 0.69 | KDM2B (0.64) | KDM4CKDM2BPHF8 | |
| SCHEMBL20978960 | 0.69 | KDM5A (0.35) | KDM4CKDM5AKDM5BKDM2BKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2019-05-08 | — | — | EP | disclosed |