Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 6/20 | 0.56 |
| ▸ | KDM4C | Q9H3R0 | 14/20 | 0.56 |
| ▸ | KDM5A | P29375 | 6/20 | 0.48 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.48 |
| ▸ | KDM4A | O75164 | 3/20 | 0.47 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.46 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20978846 | 0.93 | PHF8 (0.54) | PHF8KDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL20979069 | 0.90 | KDM4C (0.53) | PHF8KDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL20979041 | 0.89 | PHF8 (0.59) | PHF8KDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL17604562 | 0.85 | PHF8 (0.60) | PHF8KDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL20978856 | 0.85 | KDM4C (0.68) | PHF8KDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL20978873 | 0.85 | KDM4C (0.56) | PHF8KDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL19383295 | 0.85 | PHF8 (0.56) | PHF8KDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL20978901 | 0.84 | KDM4C (0.55) | PHF8KDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL24244175 | 0.84 | PHF8 (0.55) | PHF8KDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL24244164 | 0.84 | PHF8 (0.55) | PHF8KDM4CKDM5AKDM5BKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2019-05-08 | — | — | EP | disclosed |