Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 14/20 | 0.55 |
| ▸ | KDM5A | P29375 | 6/20 | 0.55 |
| ▸ | KDM5B | Q9UGL1 | 6/20 | 0.55 |
| ▸ | KDM4A | O75164 | 4/20 | 0.52 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20978753 | 0.90 | KDM4C (0.52) | KDM4CKDM5AKDM5BKDM4APHF8 | |
| SCHEMBL20979069 | 0.86 | KDM4C (0.53) | KDM4CKDM5AKDM5BKDM4APHF8 | |
| SCHEMBL16033924 | 0.85 | KDM4C (0.65) | KDM4CKDM5AKDM5BKDM4APHF8 | |
| SCHEMBL20979031 | 0.84 | PHF8 (0.56) | KDM4CKDM5AKDM5BKDM4APHF8 | |
| SCHEMBL20978846 | 0.83 | PHF8 (0.54) | KDM4CKDM5AKDM5BKDM4APHF8 | |
| SCHEMBL20979041 | 0.80 | PHF8 (0.59) | KDM4CKDM5AKDM5BKDM4APHF8 | |
| SCHEMBL20978873 | 0.80 | KDM4C (0.56) | KDM4CKDM5AKDM5BKDM4APHF8 | |
| SCHEMBL20978856 | 0.78 | KDM4C (0.68) | KDM4CKDM5AKDM5BKDM4APHF8 | |
| SCHEMBL20978701 | 0.76 | KDM4C (0.52) | KDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL20978893 | 0.75 | KDM2B (0.65) | KDM4CKDM5AKDM5BKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2019-05-08 | — | — | EP | disclosed |