Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 17/20 | 0.72 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.52 |
| ▸ | KDM5A | P29375 | 2/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20978913 | 0.93 | KDM4C (0.62) | KDM4CKDM2BKDM5AKDM5BPHF8 | |
| SCHEMBL20978965 | 0.92 | KDM4C (0.72) | KDM4CKDM2BKDM5AKDM5BKDM4A | |
| SCHEMBL16034492 | 0.84 | KDM4C (1.00) | KDM4CKDM2BKDM5AKDM5BKDM4A | |
| SCHEMBL20979071 | 0.83 | KDM4C (0.72) | KDM4CKDM2BKDM5AKDM5BKDM4A | |
| SCHEMBL20979032 | 0.81 | KDM4C (0.57) | KDM4CKDM2BKDM5AKDM5BKDM4A | |
| SCHEMBL20978863 | 0.80 | KDM4C (0.70) | KDM4CKDM2BKDM5AKDM5BKDM4A | |
| SCHEMBL19101732 | 0.79 | KDM4C (0.72) | KDM4CKDM2BKDM5AKDM5BKDM4A | |
| SCHEMBL16034273 | 0.78 | KDM4C (0.69) | KDM4CKDM2BMAPK14PHF8 | |
| SCHEMBL20978856 | 0.77 | KDM4C (0.68) | KDM4CKDM2BKDM5AKDM5BKDM4A | |
| SCHEMBL16033547 | 0.76 | KDM4C (1.00) | KDM4CKDM2BKDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2019-05-08 | — | — | EP | disclosed |