Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 15/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24019579 | 0.84 | EPHX1 (0.35) | EPHX2EPHX1CYP2C19 | |
| SCHEMBL22271235 | 0.84 | MEN1 (0.46) | EPHX2EPHX1 | |
| SCHEMBL18902629 | 0.79 | EPHX1 (0.43) | EPHX1 | |
| SCHEMBL25969203 | 0.79 | EPHX1 (0.35) | EPHX1KDM4AKDM4C | |
| SCHEMBL24098255 | 0.78 | GAA (0.34) | EPHX2EPHX1GAA | |
| SCHEMBL22221622 | 0.78 | MEN1 (0.33) | — | |
| SCHEMBL23544206 | 0.78 | EPHX2 (0.40) | EPHX2EPHX1 | |
| SCHEMBL22623220 | 0.77 | EPHX1 (0.34) | EPHX1KDM4AKDM4C | |
| SCHEMBL18902810 | 0.77 | PAOX (0.32) | GAA | |
| SCHEMBL19164322 | 0.77 | EPHX1 (0.39) | EPHX2EPHX1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057991-B1 | CHIMERIC ANTIGEN RECEPTOR T CELL SWITCHES AND USES THEREOF | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RES (US) | 2019-05-08 | — | — | EP | disclosed |