Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.30 |
| ▸ | CHRNG | P07510 | 1/20 | 0.30 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.30 |
| ▸ | CHRND | Q07001 | 1/20 | 0.30 |
| ▸ | TLR2 | O60603 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22892888 | 0.79 | MEN1 (0.33) | GAATLR2 | |
| SCHEMBL22271235 | 0.79 | MEN1 (0.46) | — | |
| SCHEMBL20979271 | 0.77 | EPHX2 (0.34) | GAA | |
| SCHEMBL26248525 | 0.77 | ALDH1A1 (0.34) | — | |
| SCHEMBL18902601 | 0.73 | KDM4A (0.39) | PAOXGAACHRNA1CHRNGCHRNB1 | |
| SCHEMBL22326266 | 0.73 | PAOX (0.41) | PAOXGAA | |
| SCHEMBL23544206 | 0.72 | EPHX2 (0.40) | — | |
| SCHEMBL25369676 | 0.72 | PAOX (0.39) | PAOXGAACHRNA1CHRNGCHRNB1 | |
| SCHEMBL3996449 | 0.71 | CA1 (0.38) | GAA | |
| SCHEMBL3998325 | 0.71 | CA1 (0.38) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3173408-A1 | PHENYL TETRAHYDROISOQUINOLINE COMPOUND SUBSTITUTED WITH HETEROARYL | Taisho Pharmaceutical Co., Ltd. (JP) | 2017-05-31 | — | — | EP | disclosed |