Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20481678 | 1.00 | CHRM1 (1.00) | CHRM1 | |
| SCHEMBL21362316 | 0.88 | CHRM1 (0.78) | CHRM1 | |
| SCHEMBL20481711 | 0.88 | CHRM1 (1.00) | CHRM1 | |
| SCHEMBL20979767 | 0.88 | CHRM1 (1.00) | CHRM1 | |
| SCHEMBL20979774 | 0.87 | CHRM1 (1.00) | CHRM1 | |
| SCHEMBL18644828 | 0.87 | CHRM1 (1.00) | CHRM1 | |
| SCHEMBL18644826 | 0.85 | CHRM1 (1.00) | CHRM1 | |
| SCHEMBL20979766 | 0.85 | CHRM1 (1.00) | CHRM1 | |
| SCHEMBL18645652 | 0.81 | CHRM1 (0.77) | CHRM1 | |
| SCHEMBL17929750 | 0.81 | CHRM1 (0.71) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10294217-B2 | Fluoroindole derivatives as muscarinic M1 receptor positive allosteric modulators | SUVEN LIFE SCIENCES LIMITED (IN) | 2019-05-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10294217-B2 | Fluoroindole derivatives as muscarinic M1 receptor positive allosteric modulators | CHRM1, CHRM2, CHRM3 | CHRM1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.