Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 13/20 | 0.78 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20979768 | 0.88 | CHRM1 (1.00) | CHRM1 | |
| SCHEMBL20481678 | 0.88 | CHRM1 (1.00) | CHRM1 | |
| SCHEMBL21362265 | 0.87 | CHRM1 (0.79) | CHRM1CNR1CNR2 | |
| SCHEMBL21362277 | 0.85 | CHRM1 (0.79) | CHRM1 | |
| SCHEMBL21362279 | 0.85 | CHRM1 (0.78) | CHRM1CNR1CNR2 | |
| SCHEMBL21362263 | 0.80 | CHRM1 (0.60) | CHRM1CNR1CNR2 | |
| SCHEMBL18645653 | 0.79 | CHRM1 (0.79) | CHRM1CNR1CNR2 | |
| SCHEMBL18614838 | 0.79 | CHRM1 (0.62) | CHRM1 | |
| SCHEMBL18646268 | 0.77 | CHRM1 (0.62) | CHRM1CNR1CNR2RAB9A | |
| SCHEMBL20481711 | 0.75 | CHRM1 (1.00) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3347349-B1 | FLUOROINDOLE DERIVATIVES AS MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | SUVEN LIFE SCIENCES LTD (IN) | 2019-09-18 | — | — | EP | disclosed |