SCHEMBL20979873

SCHEMBL20979873

CCCC[Si](C)(C)c1cccc2ccccc12

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HTR1B P28222 2/20 0.39
HTR1D P28221 1/20 0.37
ELANE P08246 1/20 0.37
TLR8 Q9NR97 2/20 0.37
ALOX15 P16050 3/20 0.36
CYP2A6 P11509 2/20 0.36
EPHX1 P07099 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20979870 0.93 KCNH2 (0.44) HTR1BTLR8ALOX15ALDH1A1MAPT
SCHEMBL15302686 0.81 EPHX1 (0.39) HTR1BHTR1DTLR8EPHX1
SCHEMBL15301975 0.81 NCEH1 (0.39) HTR1BHTR1DTLR8CYP2A6EPHX1
SCHEMBL15302196 0.78 HTR1B (0.39) HTR1BHTR1D
SCHEMBL15301792 0.77 HTR1B (0.38) HTR1BHTR1D
SCHEMBL8983908 0.76 CYP2A6 (0.40) ALOX15CYP2A6ALDH1A1
SCHEMBL15301504 0.74 CNR1 (0.36) HTR1BHTR1DTLR8EPHX1ALDH1A1
SCHEMBL15302934 0.74 KMT2A (0.39) HTR1BEPHX1ALDH1A1
SCHEMBL7284382 0.74 CNR2 (0.41) TLR8ALDH1A1MAPT
SCHEMBL19809311 0.73 CNR1 (0.43) HTR1BHTR1DTLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10295819-B1 Naphtyl based high index hydrophobic liquids and transmission recovery agents for liquid lens formulations CORNING INCORPORATED (US) 2019-05-21 US claimed
US-11204492-B2 Naphtyl based high index hydrophobic liquids and transmission recovery agents for liquid lens formulations CORNING INCORPORATED (US) 2021-12-21 US disclosed
EP-3769130-A1 NAPHTYL BASED HIGH INDEX HYDROPHOBIC LIQUIDS AND TRANSMISSION RECOVERY AGENTS FOR LIQUID LENS FORMULATIONS Corning Incorporated (US) 2021-01-27 EP disclosed
CN-111902738-A Naphthyl-based high refractive index hydrophobic liquids and transmittance restoration agents for liquid lens formulations 康宁股份有限公司 2020-11-06 CN disclosed
US-20200142180-A1 NAPHTYL BASED HIGH INDEX HYDROPHOBIC LIQUIDS AND TRANSMISSION RECOVERY AGENTS FOR LIQUID LENS FORMULATIONS CORNING INC (US) 2020-05-07 US disclosed
US-10558031-B2 Naphtyl based high index hydrophobic liquids and transmission recovery agents for liquid lens formulations CORNING INCORPORATED (US) 2020-02-11 US disclosed
US-20190293920-A1 NAPHTYL BASED HIGH INDEX HYDROPHOBIC LIQUIDS AND TRANSMISSION RECOVERY AGENTS FOR LIQUID LENS FORMULATIONS CORNING INC (US) 2019-09-26 US disclosed
US-10295819-B1 Naphtyl based high index hydrophobic liquids and transmission recovery agents for liquid lens formulations CORNING INCORPORATED (US) 2019-05-21 US disclosed