Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.41 |
| ▸ | CNR1 | P21554 | 8/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18796464 | 0.79 | CA2 (0.39) | ARTSHRALDH1A1MAPT | |
| SCHEMBL20979873 | 0.74 | HTR1B (0.39) | ALDH1A1MAPTTLR8 | |
| SCHEMBL7064746 | 0.73 | ALDH1A1 (0.34) | NR1H2NR1H3ALDH1A1 | |
| SCHEMBL556905 | 0.73 | LIPG (0.39) | CNR2CNR1NR1H2NR1H3TLR8 | |
| SCHEMBL7148124 | 0.73 | NR1H2 (0.35) | CNR2CNR1NR1H2NR1H3MEN1 | |
| SCHEMBL29444210 | 0.72 | FAAH (0.41) | CNR2NAAATSHRHTTMEN1 | |
| SCHEMBL5801979 | 0.71 | NR1H2 (0.53) | CNR2CNR1NR1H2NR1H3NAAA | |
| SCHEMBL7422836 | 0.71 | NAAA (0.40) | NAAATSHRHTTALDH1A1 | |
| SCHEMBL18796466 | 0.71 | TSHR (0.39) | TSHRALDH1A1MAPT | |
| SCHEMBL18796046 | 0.71 | NR1H2 (0.44) | NR1H2NR1H3TSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1075062-C | Acetic acid derivatives | HOFFMANN LA ROCHE (CH) | 2001-11-21 | — | — | CN | disclosed |
| EP-0656348-B1 | Aceric acid derivatives as medicaments | HOFFMANN LA ROCHE (CH) | 2000-05-03 | — | — | EP | disclosed |
| CN-1112104-A | Acetic acid derivatives | HOFFMANN LA ROCHE (CH) | 1995-11-22 | — | — | CN | disclosed |
| EP-0656348-A2 | Aceric acid derivatives as medicaments | F. HOFFMANN-LA ROCHE AG (CH) | 1995-06-07 | — | — | EP | disclosed |