Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2792653 | 0.79 | — | — | |
| SCHEMBL594483 | 0.79 | — | — | |
| SCHEMBL814779 | 0.79 | MME (0.42) | MMERAB9AACECPA1ACE2 | |
| SCHEMBL6546062 | 0.79 | MME (0.42) | MMERAB9AACECPA1ACE2 | |
| SCHEMBL594482 | 0.79 | — | — | |
| SCHEMBL43483 | 0.79 | MME (0.42) | MMERAB9AACECPA1ACE2 | |
| SCHEMBL3508862 | 0.77 | MME (0.41) | MMERAB9AACECPA1ACE2 | |
| Hydrazine SCHEMBL27924753 | 0.77 | RAB9A (0.41) | MMERAB9AACECPA1ACE2 | |
| SCHEMBL28262449 | 0.77 | MME (0.41) | MMERAB9AACECPA1ACE2 | |
| SCHEMBL596422 | 0.77 | MME (0.41) | MMERAB9AACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3037417-B1 | 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2019-05-22 | — | — | EP | disclosed |