Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2099131 | 1.00 | GABRA5 (0.60) | GABRA5 | |
| SCHEMBL285879 | 1.00 | GABRA5 (0.60) | GABRA5 | |
| SCHEMBL286046 | 0.88 | GABRA5 (0.70) | GABRA5 | |
| SCHEMBL2628064 | 0.86 | GABRA5 (0.60) | GABRA5 | |
| SCHEMBL285690 | 0.86 | GABRA5 (0.60) | GABRA5 | |
| SCHEMBL286444 | 0.85 | GABRA5 (0.60) | GABRA5 | |
| SCHEMBL291878 | 0.85 | GABRA5 (0.56) | GABRA5 | |
| SCHEMBL286292 | 0.85 | GABRA5 (0.54) | GABRA5 | |
| SCHEMBL286291 | 0.85 | GABRA5 (0.68) | GABRA5 | |
| SCHEMBL286345 | 0.84 | GABRA5 (0.56) | GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163728-B2 | Pyrazoles | HOFFMANN-LA ROCHE INC. (US) | 2012-04-24 | — | — | US | disclosed |