Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3163010 | 0.76 | ESR1 (0.48) | ESR1ACHETSHRACP3SLC6A2 | |
| SCHEMBL7783992 | 0.75 | ESR1 (0.52) | ESR1ACHETSHRACP3SLC6A2 | |
| SCHEMBL38664948 | 0.75 | ESR1 (0.52) | ESR1ACHETSHRACP3SLC6A2 | |
| SCHEMBL840826 | 0.74 | ESR1 (0.46) | ESR1ACHETSHRACP3SLC6A2 | |
| SCHEMBL9078518 | 0.74 | ESR1 (0.42) | ESR1ACHETSHRACP3SLC6A2 | |
| SCHEMBL5493731 | 0.74 | ESR1 (0.56) | ESR1ACHETSHRACP3SLC6A2 | |
| SCHEMBL29392590 | 0.74 | ESR1 (0.56) | ESR1ACHETSHRACP3SLC6A2 | |
| SCHEMBL146510 | 0.74 | ESR1 (0.56) | ESR1ACHETSHRACP3SLC6A2 | |
| SCHEMBL6546306 | 0.74 | ESR1 (0.56) | ESR1ACHETSHRACP3SLC6A2 | |
| SCHEMBL40597 | 0.74 | ESR1 (0.56) | ESR1ACHETSHRACP3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163460-B2 | Underlayer coating forming composition for lithography containing polysilane compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20080318158-A1 | Underlayer Coating Forming Composition for Lithography Containing Polysilane Compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2008-12-25 | — | — | US | disclosed |