SCHEMBL7783992

SCHEMBL7783992

Cc1ccccc1C(C)Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.52
ACHE P22303 2/20 0.45
TSHR P16473 1/20 0.45
ADRA2A P08913 2/20 0.41
ADRA2B P18089 2/20 0.41
ADRA2C P18825 1/20 0.41
ACP3 P15309 1/20 0.39
SLC6A2 P23975 2/20 0.37
SLC6A4 P31645 2/20 0.37
SLC6A3 Q01959 2/20 0.37
GAA P10253 1/20 0.37
GABRA1 P14867 1/20 0.37
GABRB2 P47870 1/20 0.37
ALDH1A1 P00352 2/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CYP3A4 P08684 2/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38664948 1.00 ESR1 (0.52) ESR1ACHETSHRADRA2AADRA2B
SCHEMBL29392590 0.83 ESR1 (0.56) ESR1ACHETSHRADRA2AADRA2B
SCHEMBL5493731 0.83 ESR1 (0.56) ESR1ACHETSHRADRA2AADRA2B
SCHEMBL40597 0.83 ESR1 (0.56) ESR1ACHETSHRADRA2AADRA2B
SCHEMBL2865478 0.83 GABRA1 (0.43) ESR1TSHRSLC6A2GABRA1GABRB2
SCHEMBL11615386 0.81 ESR1 (0.54) ESR1ACHETSHRADRA2AADRA2B
SCHEMBL258272 0.81 ESR1 (0.54) ESR1ACHETSHRADRA2AADRA2B
SCHEMBL30142944 0.81 ESR1 (0.54) ESR1ACHETSHRADRA2AADRA2B
SCHEMBL31498556 0.81 ESR1 (0.54) ESR1ACHETSHRADRA2AADRA2B
Iodide SCHEMBL29230048 0.81 ESR1 (0.54) ESR1ACHETSHRADRA2AADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020145347-A1 PRODUCTION METHOD FOR α-CHLOROETHYL BENZYL CHLORIDE AND PRODUCTION METHOD FOR CHLOROMETHYLSTYRENE 長瀬産業株式会社 2020-07-16 WO claimed
CN-1738836-B Polymerization process EXXONMOBIL CHEM PATENTS INC 2013-04-24 CN claimed
CN-100577699-C Polymers with new sequence distributions EXXONMOBIL CHEM PATENTS INC 2010-01-06 CN claimed
CN-100569812-C Has the polymkeric substance that new sequence distributes EXXONMOBIL CHEM PATENTS INC (US) 2009-12-16 CN claimed
CN-100427512-C Polymerization processes EXXONMOBIL CHEM PATENTS INC (US) 2008-10-22 CN claimed
CN-100402565-C Polymer without long branched chain EXXONMOBIL CHEM PATENTS INC (US) 2008-07-16 CN claimed
CN-100402558-C Polymerization processes EXXONMOBIL CHEM PATENTS INC (US) 2008-07-16 CN claimed
CN-1332986-C Polymerization processes EXXONMOBIL CHEM PATENTS INC (US) 2007-08-22 CN claimed
CN-1972974-A Polymerization process using hydrofluorocarbons EXXONMOBIL CHEM PATENTS INC (US) 2007-05-30 CN claimed
CN-1753918-A Polymer without long branched chain EXXONMOBIL CHEM PATENTS INC (US) 2006-03-29 CN claimed
CN-1738843-A Polymers with novel sequence distributions EXXONMOBIL CHEM PATENTS INC (US) 2006-02-22 CN claimed
CN-1738836-A Polymerization process EXXONMOBIL CHEM PATENTS INC (US) 2006-02-22 CN claimed
CN-1729204-A Polymerization processes EXXONMOBIL CHEM PATENTS INC (US) 2006-02-01 CN claimed
CN-1729208-A Polymerization processes EXXONMOBIL CHEM PATENTS INC (US) 2006-02-01 CN claimed
CN-1729215-A Polymers with new sequence distributions EXXONMOBIL CHEM PATENTS INC (US) 2006-02-01 CN claimed
CN-1729209-A Polymerization processes EXXONMOBIL CHEM PATENTS INC (US) 2006-02-01 CN claimed
US-3962357-A FROM SUBSTITUTED ETHYLTOLUENE, CONTINUOUS, SINGLE STEP ROHM AND HAAS COMPANY (US) 1976-06-08 US claimed
US-12435078-B2 Pyridazinones and methods of use thereof GFB (ABC), LLC (US) 2025-10-07 US disclosed
EP-0017455-A1 Linear crystalline alpha-alkylpolybenzyls and process for preparing them EXXON RESEARCH AND ENGINEERING COMPANY (US) 1980-10-15 EP disclosed
US-3962357-A FROM SUBSTITUTED ETHYLTOLUENE, CONTINUOUS, SINGLE STEP ROHM AND HAAS COMPANY (US) 1976-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12435078-B2 Pyridazinones and methods of use thereof PDXK, ATP6V1B1, REN ESR1 4397/4885ACHE 403/4885TSHR 1945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.