SCHEMBL20986992

SCHEMBL20986992

Cc1cccc(C)c1CNc1cc(C(=O)N2CCC2)cn2c(C)c(C)nc12

nearest known ligand 0.67

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 20/20 0.67
CYP2C9 P11712 20/20 0.67
CYP2D6 P10635 10/20 0.67
CYP2C19 P33261 8/20 0.64
CYP1A2 P05177 7/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrophosphoric Acid SCHEMBL31756913 0.93 CYP3A4 (0.61) CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2
SCHEMBL27523706 0.92 CYP3A4 (0.75) CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2
SCHEMBL21014314 0.91 CYP3A4 (0.64) CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2
SCHEMBL21014844 0.91 CYP3A4 (0.64) CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2
Citric Acid SCHEMBL27075566 0.91 CYP3A4 (0.56) CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2
SCHEMBL20987001 0.90 CYP3A4 (0.54) CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2
SCHEMBL20987002 0.89 CYP3A4 (0.53) CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2
SCHEMBL20987005 0.88 CYP3A4 (0.65) CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2
SCHEMBL20987023 0.88 CYP3A4 (0.65) CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2
SCHEMBL20987027 0.88 CYP3A4 (0.52) CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122075420-A Imidazo [1,2-a ] pyridine derivative pharmaceutical composition and application thereof 2026-05-26 CN claimed
EP-4563577-A1 NOVEL SALT OF IMIDAZO[1,2-A]PYRIDINE COMPOUND, CRYSTALLINE FORM THEREOF, AND PREPARATION METHOD Jeil Pharmaceutical Co., Ltd. (KR) 2025-06-04 EP claimed
WO-2024161317-A1 PHARMACEUTICAL FORMULATION, PREPARATION METHOD THEREFOR, AND TABLET COMPOSITION 제일약품주식회사 2024-08-08 WO claimed
EP-3481827-B1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES, METHODS FOR PREPARING THE SAME AND USE THEREOF JEIL PHARMACEUTICAL CO LTD (KR) 2021-11-03 EP claimed
US-20190152971-A1 Imidazo[1,2-A]Pyridine Derivatives, Methods for Preparing the Same and Use Thereof JEIL PHARMACEUTICAL CO., LTD. (KR) 2019-05-23 US claimed
CN-122075420-A Imidazo [1,2-a ] pyridine derivative pharmaceutical composition and application thereof 2026-05-26 CN disclosed
CN-121127240-A Imidazo [1,2-a ] pyridine derivative pharmaceutical composition, preparation method and application thereof 丽珠医药集团股份有限公司 2025-12-12 CN disclosed
EP-4658244-A1 INJECTABLE COMPOSITION, PHARMACEUTICAL FORMULATION INCLUDING THE SAME, AND METHOD FOR PREPARING THE COMPOSITION Onconic Therapeutics Inc. (KR) 2025-12-10 EP disclosed
CN-120827558-A Imidazo [1,2-a ] pyridine derivative pharmaceutical composition, preparation method and application thereof 丽珠医药集团股份有限公司 2025-10-24 CN disclosed
WO-2025215593-A1 AN IMPROVED PROCESS FOR PREPARATION OF ZASTAPRAZAN HETERO LABS LIMITED (IN) 2025-10-16 WO disclosed
WO-2024161317-A1 PHARMACEUTICAL FORMULATION, PREPARATION METHOD THEREFOR, AND TABLET COMPOSITION 제일약품주식회사 2024-08-08 WO disclosed
WO-2024161316-A1 INJECTABLE COMPOSITION, PHARMACEUTICAL FORMULATION INCLUDING THE SAME, AND METHOD FOR PREPARING THE COMPOSITION ONCONIC THERAPEUTICS INC. (KR) 2024-08-08 WO disclosed
WO-2024117797-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF DRUG-RELATED PEPTIC ULCER COMPRISING ZASTAPRAZAN OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF 제일약품 주식회사 2024-06-06 WO disclosed
WO-2024117798-A1 COMPOSITION FOR REMOVING HELICOBACTER PYLORI COMPRISING ZASTAPRAZAN OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF 제일약품 주식회사 2024-06-06 WO disclosed
WO-2024025393-A1 NOVEL SALT OF IMIDAZO[1,2-A]PYRIDINE COMPOUND, CRYSTALLINE FORM THEREOF, AND PREPARATION METHOD 제일약품주식회사 2024-02-01 WO disclosed
US-10696671-B2 Imidazo[1,2-A]pyridine derivatives, methods for preparing the same and use thereof JEIL PHARMACEUTICAL CO., LTD. (KR) 2020-06-30 US disclosed
US-10696671-B2 Imidazo[1,2-A]pyridine derivatives, methods for preparing the same and use thereof JEIL PHARMACEUTICAL CO., LTD. (KR) 2020-06-30 US disclosed
US-20190152971-A1 Imidazo[1,2-A]Pyridine Derivatives, Methods for Preparing the Same and Use Thereof JEIL PHARMACEUTICAL CO., LTD. (KR) 2019-05-23 US disclosed
US-20190152971-A1 Imidazo[1,2-A]Pyridine Derivatives, Methods for Preparing the Same and Use Thereof JEIL PHARMACEUTICAL CO., LTD. (KR) 2019-05-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10696671-B2 Imidazo[1,2-A]pyridine derivatives, methods for preparing the same and use thereof HRH2, GIPR, HRH4 CYP3A4 145/4885CYP2C9 477/4885CYP2D6 327/4885
US-20190152971-A1 Imidazo[1,2-A]Pyridine Derivatives, Methods for Preparing the Same and Use Thereof GIPR, PGC, VIP CYP3A4 987/4885CYP2C9 1375/4885CYP2D6 2024/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.