Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TLR4 | O00206 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23228558 | 0.81 | MEN1 (0.46) | MEN1KMT2ATLR4ALDH1A1SMN1; SMN2 | |
| SCHEMBL16609900 | 0.79 | MEN1 (0.47) | MEN1KMT2ATLR4ALDH1A1SMN1; SMN2 | |
| SCHEMBL20988214 | 0.78 | MEN1 (0.46) | MEN1KMT2ATLR4ALDH1A1SMN1; SMN2 | |
| SCHEMBL15427994 | 0.78 | MEN1 (0.49) | MEN1KMT2ATLR4ALDH1A1SMN1; SMN2 | |
| SCHEMBL940891 | 0.75 | KMT2A (0.47) | MEN1KMT2ATLR4ALDH1A1SMN1; SMN2 | |
| SCHEMBL12988948 | 0.72 | TLR4 (0.42) | MEN1KMT2ATLR4ALDH1A1SMN1; SMN2 | |
| SCHEMBL15325151 | 0.72 | TLR4 (0.42) | MEN1KMT2ATLR4ALDH1A1SMN1; SMN2 | |
| SCHEMBL3913430 | 0.72 | MEN1 (0.52) | MEN1KMT2ATLR4ALDH1A1SMN1; SMN2 | |
| SCHEMBL20980058 | 0.72 | TLR4 (0.41) | MEN1KMT2ATLR4ALDH1A1SMN1; SMN2 | |
| SCHEMBL20955890 | 0.71 | MAPT (0.43) | MEN1KMT2ATLR4ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10745354-B2 | Methods for enantioselective allylic alkylation of esters, lactones, and lactams with unactivated allylic alcohols | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2020-08-18 | — | — | US | disclosed |
| US-20200048201-A1 | METHODS FOR ENANTIOSELECTIVE ALLYLIC ALKYLATION OF ESTERS, LACTONES, AND LACTAMS WITH UNACTIVATED ALLYLIC ALCOHOLS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2020-02-13 | — | — | US | disclosed |
| US-10358422-B2 | Methods for enantioselective allylic alkylation of esters, lactones, and lactams with unactivated allylic alcohols | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2019-07-23 | — | — | US | disclosed |
| US-20190135754-A1 | METHODS FOR ENANTIOSELECTIVE ALLYLIC ALKYLATION OF ESTERS, LACTONES, AND LACTAMS WITH UNACTIVATED ALLYLIC ALCOHOLS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2019-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200048201-A1 | METHODS FOR ENANTIOSELECTIVE ALLYLIC ALKYLATION OF ESTERS, LACTONES, AND LACTAMS WITH UNACTIVATED ALLYLIC ALCOHOLS | LSS, COASY, ADH1A | MEN1 273/4885KMT2A 1584/4885TLR4 4238/4885 |
| US-20190135754-A1 | METHODS FOR ENANTIOSELECTIVE ALLYLIC ALKYLATION OF ESTERS, LACTONES, AND LACTAMS WITH UNACTIVATED ALLYLIC ALCOHOLS | LSS, COASY, ADH1A | MEN1 273/4885KMT2A 1584/4885TLR4 4238/4885 |
| US-10745354-B2 | Methods for enantioselective allylic alkylation of esters, lactones, and lactams with unactivated allylic alcohols | LSS, COASY, ADH1A | MEN1 273/4885KMT2A 1584/4885TLR4 4238/4885 |
| US-10358422-B2 | Methods for enantioselective allylic alkylation of esters, lactones, and lactams with unactivated allylic alcohols | LSS, COASY, ADH1A | MEN1 273/4885KMT2A 1584/4885TLR4 4238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.