Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphine SCHEMBL10495866 | 0.68 | TSHR (0.32) | TSHR | |
| SCHEMBL8452318 | 0.67 | TSHR (0.31) | TSHR | |
| SCHEMBL9307060 | 0.65 | TSHR (0.30) | TSHR | |
| SCHEMBL8143353 | 0.63 | — | — | |
| SCHEMBL9926752 | 0.63 | TSHR (0.31) | TSHR | |
| SCHEMBL23419456 | 0.61 | TSHR (0.30) | TSHR | |
| SCHEMBL1402719 | 0.61 | TDP1 (0.31) | TSHR | |
| SCHEMBL7858703 | 0.61 | TSHR (0.30) | TSHR | |
| SCHEMBL252367 | 0.61 | TSHR (0.30) | TSHR | |
| SCHEMBL7262903 | 0.61 | TSHR (0.30) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163891-B2 | Process for the preparation of poly(alkoxylated) oligonucleotides | AVECIA BIOTECHNOLOGY INC (US) | 2012-04-24 | — | — | US | disclosed |
| EP-1963351-B1 | PROCESS FOR THE PREPARATION OF POLY(ALKOXYLATED) OLIGONUCLEOTIDES | AVECIA BIOTECHNOLOGY INC (US) | 2010-07-28 | — | — | EP | disclosed |
| US-20100029924-A1 | Process for the Preparation of Poly(Alkoxylated) Oligonucleotides | NITTO DENKO AVECIA, INC. | 2010-02-04 | — | — | US | disclosed |
| EP-1963351-A2 | PROCESS FOR THE PREPARATION OF POLY(ALKOXYLATED) OLIGONUCLEOTIDES | Avecia Biotechnology Inc (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007066069-A2 | PROCESS FOR THE PREPARATION OF POLY(ALKOXYLATED) OLIGONUCLEOTIDES | AVECIA BIOTECHNOLOGY INC. (US) | 2007-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029924-A1 | Process for the Preparation of Poly(Alkoxylated) Oligonucleotides | PUF60, POLRMT, POLI | TSHR 4098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.