Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.67 |
| ▸ | RAB9A | P51151 | 7/20 | 0.67 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.65 |
| ▸ | GRM4 | Q14833 | 6/20 | 0.65 |
| ▸ | PKM | P14618 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MITF | O75030 | 1/20 | 0.61 |
| ▸ | KDR | P35968 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28790184 | 0.85 | NPSR1 (0.57) | NPC1RAB9ATLR7SMN1; SMN2GRM4 | |
| SCHEMBL231897 | 0.85 | KDR (0.78) | NPC1RAB9ASMN1; SMN2GRM4PKM | |
| SCHEMBL28871740 | 0.85 | TLR7 (0.70) | NPC1RAB9ATLR7SMN1; SMN2GRM4 | |
| SCHEMBL338860 | 0.85 | TLR7 (0.57) | NPC1RAB9ATLR7SMN1; SMN2GRM4 | |
| SCHEMBL28947571 | 0.84 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2GRM4PKM | |
| SCHEMBL29184186 | 0.84 | KDR (0.76) | NPC1RAB9ASMN1; SMN2GRM4PKM | |
| SCHEMBL674215 | 0.83 | HDAC2 (0.62) | NPC1RAB9ATLR7SMN1; SMN2GRM4 | |
| SCHEMBL18993402 | 0.83 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2GRM4PKM | |
| SCHEMBL10415452 | 0.83 | GRM4 (0.65) | NPC1RAB9ASMN1; SMN2GRM4PKM | |
| SCHEMBL7988912 | 0.83 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2GRM4PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111690947-B | Electrochemical synthesis method of trifluoromethylated aryl amide derivative | 浙江工业大学 | 2021-10-15 | — | — | CN | disclosed |
| EP-3480199-B1 | IMIDAZOPYRIDINAMINE PHENYL DERIVATIVE AND USE THEREOF | HANGZHOU BANGSHUN PHARMACEUTICAL CO LTD (CN) | 2021-03-17 | — | — | EP | disclosed |
| CN-111690947-A | Electrochemical synthesis method of trifluoromethylated aryl amide derivative | 浙江工业大学 | 2020-09-22 | — | — | CN | disclosed |
| EP-3480199-A1 | IMIDAZOPYRIDINAMINE PHENYL DERIVATIVE AND USE THEREOF | Hangzhou Sanyintai Pharmaceutical Technology Co., Ltd. (CN) | 2019-05-08 | — | — | EP | disclosed |