SCHEMBL231897

SCHEMBL231897

O=C(Nc1ccccc1)c1ccccn1

nearest known ligand 0.78

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDR P35968 5/20 0.78
KCNK3 O14649 1/20 0.73
KCNK9 Q9NPC2 1/20 0.73
GRM4 Q14833 7/20 0.70
HDAC6 Q9UBN7 1/20 0.70
POLB P06746 1/20 0.69
NPC1 O15118 6/20 0.68
RAB9A P51151 6/20 0.68
SMN1; SMN2 Q16637 6/20 0.68
MAPT P10636 2/20 0.68
PKM P14618 2/20 0.68
CCR6 P51684 1/20 0.65
KMT2A Q03164 1/20 0.65
NPSR1 Q6W5P4 1/20 0.65
KDM4E B2RXH2 1/20 0.64
MITF O75030 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29184186 0.98 KDR (0.76) KDRKCNK3KCNK9GRM4HDAC6
SCHEMBL12469044 0.89 NPC1 (0.64) KDRKCNK3KCNK9GRM4HDAC6
SCHEMBL29581099 0.89 NPC1 (0.64) KDRKCNK3KCNK9GRM4HDAC6
SCHEMBL7990375 0.89 KDR (0.84) KDRKCNK3KCNK9GRM4HDAC6
SCHEMBL9379519 0.88 KDR (0.72) KDRKCNK3KCNK9GRM4HDAC6
SCHEMBL30693673 0.88 NPC1 (0.63) KDRKCNK3KCNK9GRM4NPC1
SCHEMBL4323035 0.88 NPC1 (0.63) KDRKCNK3KCNK9GRM4NPC1
SCHEMBL28947571 0.87 NPC1 (0.67) KDRKCNK3KCNK9GRM4HDAC6
SCHEMBL30986144 0.86 KDR (0.74) KDRKCNK3KCNK9GRM4HDAC6
SCHEMBL6037590 0.85 KDR (0.78) KDRGRM4NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119751827-A Bis (4-phenyl) pyridinamine polymer and preparation method and application thereof 链行走新材料科技(广州)有限公司 2025-04-04 CN claimed
CN-118005608-A Triazole small molecular organic compound for inhibiting mitochondrial oxidative phosphorylation by specific targeting complex I and application thereof 华东师范大学 2024-05-10 CN claimed
EP-4006035-B1 QUINAZOLINE DERIVATIVES AS TYROSINE KINASE INHIBITORS FOR THE TREATMENT OF CANCER NEUPHARMA INC (US) 2023-11-22 EP claimed
CN-116870968-B Iridium complex functionalized nano graphene catalyst, and preparation method and application thereof 烟台大学 2023-11-10 CN claimed
CN-116870968-A Iridium complex functionalized nano graphene catalyst, and preparation method and application thereof 烟台大学 2023-10-13 CN claimed
CN-112715566-B Herbicide for sealing lawn weeds before germination and preparation method thereof 南京农业大学 2021-08-31 CN claimed
CN-112715566-A Herbicide for sealing lawn weeds before germination and preparation method thereof 南京农业大学 2021-04-30 CN claimed
CN-106349156-B It can be used as the pyridine -2- amides of CB2 agonist 霍夫曼-拉罗奇有限公司 2018-12-11 CN claimed
CN-104540825-B Azaindole quinoline compound 霍夫曼-拉罗奇有限公司 2017-10-24 CN claimed
CN-103756670-A Organic electroluminescence material as well as preparation method and application thereof SHANGHAI EVERDISPLAY OPTRONICS CO LTD 2014-04-30 CN claimed
CN-1845673-A Pyridylacanilides BAYER CROPSCIENCE AG (DE) 2006-10-11 CN claimed
US-20060178513-A1 Pyridinylanilides BAYER CROPSCIENCE AG (DE) 2006-08-10 US claimed
EP-1656020-A2 PYRIDINYLANILIDES Bayer CropScience AG (DE) 2006-05-17 EP claimed
EP-1537106-A1 DIHYDROPYRAZOLOPYRIDINE COMPOUNDS Mitsubishi Pharma Corporation (JP) 2005-06-08 EP claimed
WO-2005004606-A2 PYRIDINYLANILIDES BAYER CROPSCIENCE AG (DE) 2005-01-20 WO claimed
WO-2004014910-A1 DIHYDROPYRAZOLOPYRIDINE COMPOUNDS MITSUBISHI PHARMA CORPORATION (JP) 2004-02-19 WO claimed
CN-1136180-C Preparation of aryl methyl ketone 四川大学 2004-01-28 CN claimed
US-6680385-B2 SOLVENT-FREE OXIDATION OF ETHYL ARENES USING AIR MIXTURES AS OXIDIZERS, IN THE PRESENCE OF METAL COMPLEXES HAVING CATALYST SELECTIVITY AND EFFICIENCY THE HONG KONG POLYTECHNIC UNIVERSITY (HK) 2004-01-20 US claimed
CN-1297881-A Preparation of aryl methyl ketone UNIV SICHUAN (CN) 2001-06-06 CN claimed
US-4493729-A HERBICIDES RHONE-POULENC AGROCHIMIE (FR) 1985-01-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060178513-A1 Pyridinylanilides C3AR1, C5, PADI1 KDR 1566/4885KCNK3 2328/4885KCNK9 3702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.