SCHEMBL2099018

SCHEMBL2099018

C[Si](C)OC(C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2839156 0.75 ALDH1A1 (0.33)
SCHEMBL1896024 0.70 ALDH1A1 (0.36)
SCHEMBL6830168 0.65
SCHEMBL232180 0.64 TDP1 (0.31)
SCHEMBL9113388 0.64 TSHR (0.31)
SCHEMBL10644535 0.62 ALDH1A1 (0.38)
SCHEMBL232181 0.60
SCHEMBL3291601 0.60
SCHEMBL23754128 0.52 ALDH1A1 (0.36)
SCHEMBL14688552 0.52 ALDH1A1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100582106-C Pyrrolidine sulfsulopenem derivative preparation method and its intermediate SHANGHAI INST PHARM INDUSTRY 2010-01-20 CN claimed
US-7297807-B1 Intermediates for the synthesis of polypropionate antibiotics THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2007-11-20 US claimed
CN-101007806-A Pyrrolidine sulfsulopenem derivative preparation method and its intermediate SHANGHAI INST PHARM INDUSTRY (CN) 2007-08-01 CN claimed
EP-0528678-B1 A pyrrolidylthiocarbapenem derivative with antibacterial activity SHIONOGI & CO (JP) 2001-05-23 EP claimed
CN-1032257-C Process for producing pyrrolidinethinyl carbapenem derivatives SHIONOGI SEIYAKU KK (JP) 1996-07-10 CN claimed
US-5317016-A Pyrrolidylthiocarbapenem derivative SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1994-05-31 US claimed
CN-1071428-A Pyrrolidinylthiocarbapenem derivatives SHIONOGI & CO (JP) 1993-04-28 CN claimed
EP-0528678-A1 A pyrrolidylthiocarbapenem derivative SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI &amp; CO. LTD. (JP) 1993-02-24 EP claimed
US-12037438-B2 Star polymers having a silyl coupling Johannes Gutenberg-Universität Mainz (DE) 2024-07-16 US disclosed
CN-114796533-B Marking precursors with squaric acid linkages SCV-特种化学品销售有限公司 2024-01-26 CN disclosed
US-11833229-B2 Labeling precursors with squaric acid coupling SCV SPEZIAL-CHEMIKALIEN-VERTRIEBS GMBH (DE) 2023-12-05 US disclosed
US-20220331456-A1 LABELING PRECURSORS WITH SQUARIC ACID COUPLING SCV - SpezialChemikalienVertrieb GmbH (DE) 2022-10-20 US disclosed
CN-114796533-A Mark precursors with squaric acid linkage SCV-特种化学品销售有限公司 2022-07-29 CN disclosed
US-20210369877-A1 MARKING PRECURSOR WITH SQUARIC ACID COUPLING SCV- Spezial Chemikalien Vertrieb GmbH (DE) 2021-12-02 US disclosed
US-6743885-B2 MIXTURE OF POLYSILSESQUIOXANE AND ACID GENERATOR SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-06-01 US disclosed
US-20030222242-A1 Liquid crystalline gel composition, and display medium, display device and display body using same RICOH COMPANY, LTD. (JP) 2003-12-04 US disclosed
CN-1110305-C Naphthyl-substituted benzimidazole derivatives as anticoagulants BERLEX LAB (US) 2003-06-04 CN disclosed
US-20030092854-A1 Resin composition for intermediate layer of three-layer resist SUMITOMO CHEMICAL COMPANY, LIMITED 2003-05-15 US disclosed
CN-1336902-A method for producing fluorinated silicon compound MITSUI CHEMICALS INC (JP) 2002-02-20 CN disclosed
CN-1209062-A Naphthyl-substituted benzimidazole derivatives as anticoagulants BERLEX LAB (US) 1999-02-24 CN disclosed