Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 10/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.37 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19707061 | 1.00 | KCNH2 (0.39) | KCNH2SLC2A1KCNQ1CACNA1C | |
| SCHEMBL19707063 | 1.00 | KCNH2 (0.39) | KCNH2SLC2A1KCNQ1CACNA1C | |
| SCHEMBL20996021 | 0.94 | KCNH2 (0.39) | KCNH2SLC2A1KCNQ1CACNA1C | |
| SCHEMBL20996020 | 0.94 | KCNH2 (0.39) | KCNH2SLC2A1KCNQ1CACNA1C | |
| SCHEMBL19708645 | 0.91 | KCNH2 (0.35) | KCNH2SLC2A1 | |
| SCHEMBL19706841 | 0.91 | KCNH2 (0.35) | KCNH2SLC2A1 | |
| SCHEMBL20995977 | 0.91 | SLC2A1 (0.34) | KCNH2SLC2A1KCNQ1CACNA1C | |
| SCHEMBL19706897 | 0.91 | SLC2A1 (0.34) | KCNH2SLC2A1KCNQ1CACNA1C | |
| SCHEMBL19706895 | 0.91 | SLC2A1 (0.34) | KCNH2SLC2A1KCNQ1CACNA1C | |
| SCHEMBL19706892 | 0.90 | SLC2A1 (0.35) | KCNH2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10640488-B2 | Antibacterial compounds | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2020-05-05 | — | — | US | disclosed |
| US-10633366-B2 | Antibacterial compounds | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2020-04-28 | — | — | US | disclosed |
| EP-3468975-B1 | NEW ANTIBACTERIAL COMPOUNDS | ACRAF (IT) | 2020-04-01 | — | — | EP | disclosed |
| US-20200095225-A9 | NEW ANTIBACTERIAL COMPOUNDS | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2020-03-26 | — | — | US | disclosed |
| US-20190256495-A1 | NEW ANTIBACTERIAL COMPOUNDS | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2019-08-22 | — | — | US | disclosed |
| US-20190161472-A1 | NEW ANTIBACTERIAL COMPOUNDS | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2019-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190161472-A1 | NEW ANTIBACTERIAL COMPOUNDS | MRPL21, LAS1L, MRPL19 | KCNH2 2657/4885SLC2A1 4456/4885KCNQ1 2930/4885 |
| US-20200095225-A9 | NEW ANTIBACTERIAL COMPOUNDS | MRPL21, CLPP, NRDC | KCNH2 3913/4885SLC2A1 4408/4885KCNQ1 2653/4885 |
| US-10633366-B2 | Antibacterial compounds | MRPL21, LAS1L, MRPL19 | KCNH2 2772/4885SLC2A1 4448/4885KCNQ1 3084/4885 |
| US-20190256495-A1 | NEW ANTIBACTERIAL COMPOUNDS | MRPL21, CLPP, NRDC | KCNH2 3913/4885SLC2A1 4408/4885KCNQ1 2653/4885 |
| US-10640488-B2 | Antibacterial compounds | MRPL21, CLPP, NRDC | KCNH2 3933/4885SLC2A1 4378/4885KCNQ1 3241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.