Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 10/20 | 0.47 |
| ▸ | PNP | P00491 | 8/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EDNRA | P25101 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLG | P54098 | 2/20 | 0.45 |
| ▸ | POLA1 | P09884 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3857906 | 0.82 | HPRT1 (0.66) | HPRT1PNPPOLB | |
| SCHEMBL3857910 | 0.81 | HPRT1 (0.53) | HPRT1PNPUSP2TSHREDNRA | |
| SCHEMBL17197636 | 0.80 | HPRT1 (0.54) | HPRT1PNPPOLBUSP2TSHR | |
| SCHEMBL17194164 | 0.79 | HPRT1 (0.52) | HPRT1PNPPOLBUSP2TSHR | |
| SCHEMBL15078165 | 0.78 | POLB (0.73) | HPRT1PNPPOLBUSP2TSHR | |
| SCHEMBL6834577 | 0.77 | PNP (0.56) | HPRT1PNPPOLBUSP2TSHR | |
| SCHEMBL15078309 | 0.77 | MEN1 (0.51) | HPRT1PNPUSP2TSHREDNRA | |
| SCHEMBL7627167 | 0.77 | PNP (0.58) | HPRT1PNPPOLBUSP2TSHR | |
| SCHEMBL3857914 | 0.77 | HPRT1 (0.53) | HPRT1PNPPOLB | |
| SCHEMBL8760975 | 0.76 | PNP (0.45) | HPRT1PNPPOLBUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794624-B1 | GUANINE ANALOGS AS TELOMERASE SUBSTRATES AND TELOMERE LENGTH AFFECTORS | GERON CORP (US) | 2019-05-15 | — | — | EP | disclosed |