Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 17/20 | 0.83 |
| ▸ | BCR | P11274 | 15/20 | 0.83 |
| ▸ | PDGFRA | P16234 | 12/20 | 0.83 |
| ▸ | PDGFRB | P09619 | 11/20 | 0.83 |
| ▸ | SRC | P12931 | 7/20 | 0.81 |
| ▸ | PRKCA | P17252 | 6/20 | 0.81 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.81 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.81 |
| ▸ | PRKCG | P05129 | 1/20 | 0.81 |
| ▸ | PRKCB | P05771 | 1/20 | 0.81 |
| ▸ | PRKCH | P24723 | 1/20 | 0.81 |
| ▸ | PRKCI | P41743 | 1/20 | 0.81 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.81 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.81 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.81 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.81 |
| ▸ | ABL2 | P42684 | 2/20 | 0.80 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.69 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.69 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763 | 0.91 | ABL1 (1.00) | ABL1BCRPDGFRAPDGFRBSRC | |
| SCHEMBL9197 | 0.89 | ABL1 (1.00) | ABL1BCRPDGFRAPDGFRBSRC | |
| SCHEMBL1430 | 0.89 | ABL1 (1.00) | ABL1BCRPDGFRAPDGFRBSRC | |
| SCHEMBL9565 | 0.89 | ABL1 (1.00) | ABL1BCRPDGFRAPDGFRBSRC | |
| SCHEMBL20204862 | 0.89 | ABL1 (1.00) | ABL1BCRPDGFRAPDGFRBSRC | |
| SCHEMBL10208 | 0.89 | ABL1 (0.82) | ABL1BCRPDGFRAPDGFRBSRC | |
| SCHEMBL1522 | 0.88 | ABL1 (1.00) | ABL1BCRPDGFRAPDGFRBSRC | |
| SCHEMBL4901151 | 0.88 | ABL1 (0.80) | ABL1BCRPDGFRAPDGFRBSRC | |
| SCHEMBL20204860 | 0.87 | MAPK8 (0.79) | ABL1BCRPDGFRAPDGFRBSRC | |
| SCHEMBL14979753 | 0.86 | PDGFRA (0.79) | ABL1BCRPDGFRAPDGFRBSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2822935-B1 | INHIBITORS OF C-JUN-N-TERMINAL KINASE (JNK) | DANA FARBER CANCER INST INC (US) | 2019-05-15 | — | — | EP | disclosed |