Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 14/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | LPO | P22079 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6027678 | 0.76 | TYMP (0.46) | TYMPATMALDH1A1KDM4EGAA | |
| SCHEMBL27816353 | 0.73 | TYMP (0.45) | TYMPATMALDH1A1KDM4EGAA | |
| SCHEMBL28263643 | 0.73 | TYMP (0.43) | TYMPATMALDH1A1KDM4EGAA | |
| SCHEMBL12702529 | 0.70 | TYMP (0.41) | TYMPATMALDH1A1KDM4EGAA | |
| SCHEMBL4960409 | 0.70 | POLB (0.46) | TYMPATMALDH1A1KDM4EGAA | |
| SCHEMBL15469004 | 0.70 | POLB (0.43) | TYMPATMALDH1A1KDM4EGAA | |
| SCHEMBL8768819 | 0.68 | TYMP (0.44) | TYMPATMALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL9191218 | 0.68 | ATM (0.44) | TYMPATMALDH1A1KDM4EGAA | |
| SCHEMBL24420566 | 0.68 | SMN1; SMN2 (0.46) | ALDH1A1KDM4EGAACA1LPO | |
| SCHEMBL4469664 | 0.67 | KDM4E (0.45) | TYMPATMALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265626-B1 | NUCLEOTIDE ANALOGUES WITH QUATERNARY CARBON STEREOGENIC CENTERS AND METHODS OF USE | LCB PHARMA INC (CA) | 2019-05-15 | — | — | EP | disclosed |