SCHEMBL4960409

SCHEMBL4960409

CCn1c(C)cc(=O)[nH]c1=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.46
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
CYP1A2 P05177 3/20 0.44
CYP3A4 P08684 3/20 0.44
LMNA P02545 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
CYP2D6 P10635 1/20 0.44
TSHR P16473 1/20 0.44
NFKB1 P19838 1/20 0.44
BLM P54132 1/20 0.44
PMP22 Q01453 1/20 0.44
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 4/20 0.41
TYMP P19971 4/20 0.41
ATM Q13315 1/20 0.41
HPGD P15428 1/20 0.40
GAA P10253 1/20 0.39
MAPT P10636 2/20 0.39
PDE4A P27815 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4770765 0.88 PGR (0.48) POLBMEN1KMT2ACYP1A2CYP3A4
SCHEMBL4469664 0.84 KDM4E (0.45) MEN1KMT2ALMNASMN1; SMN2BLM
SCHEMBL8768819 0.82 TYMP (0.44) MEN1KMT2ACYP3A4SMN1; SMN2KDM4E
SCHEMBL1702029 0.81 MAPT (0.45) MEN1KMT2ALMNATSHRKDM4E
SCHEMBL27385314 0.80 ATM (0.43) MEN1KMT2ACYP3A4SMN1; SMN2KDM4E
SCHEMBL18072360 0.79 HSD17B10 (0.53) MEN1KMT2ALMNAKDM4EALDH1A1
SCHEMBL29776965 0.79 B3GNT2 (0.43) MEN1KMT2ACYP1A2CYP3A4LMNA
SCHEMBL9257137 0.78 KMT2A (0.51) POLBMEN1KMT2ACYP1A2CYP3A4
SCHEMBL243853 0.78 KMT2A (0.59) POLBMEN1KMT2ACYP1A2CYP3A4
SCHEMBL11929236 0.78 KMT2A (0.43) POLBMEN1KMT2ACYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7132229-B2 Photothermographic material and image forming method FUJI PHOTO FILM CO., LTD (JP) 2006-11-07 US claimed
US-20060019207-A1 Photothermographic material and image forming method FUJIFILM CORPORATION (JP) 2006-01-26 US claimed
US-20110092451-A1 NUCLEOTIDE ANALOGUES WITH QUATERNARY CARBON STEREOGENIC CENTERS AND METHODS OF USE INSTITUT DE RECHERCHES CLINIQUES DE MONTREAL (CA) 2011-04-21 US disclosed
US-20100311175-A1 MASS TAGS FOR QUANTITATIVE ANALYSES Life Technologies Corporation (US) 2010-12-09 US disclosed
US-7410752-B2 Method of producing organic silver salt dispersion, and photothermographic material FUJIFILM CORPORATION (JP) 2008-08-12 US disclosed
US-7332267-B2 Photothermographic material FUJIFILM CORPORATION (JP) 2008-02-19 US disclosed
US-20070020566-A1 Photothermographic material and image forming method FUJI PHOTO FILM., LTD. 2007-01-25 US disclosed
US-20070015095-A1 Photothermographic material FUJI PHOTO FILM CO., LTD. 2007-01-18 US disclosed
US-7132229-B2 Photothermographic material and image forming method FUJI PHOTO FILM CO., LTD (JP) 2006-11-07 US disclosed
US-7112401-B2 Photothermographic material and image forming method using the same FUJI PHOTO FILM CO., LTD. (JP) 2006-09-26 US disclosed
US-7108965-B2 Photothermographic material and image forming method using the same FUJI PHOTO FILM CO., LTD. (JP) 2006-09-19 US disclosed
US-20060046216-A1 Photothermographic material and image forming method FUJIFILM CORPORATION (JP) 2006-03-02 US disclosed
US-20060035179-A1 Photothermographic material and image forming method using same FUJI PHOTO FILM CO., LTD. 2006-02-16 US disclosed
US-20060035180-A1 Photothermographic material and image forming method using the same FUJI PHOTO FILM CO., LTD. 2006-02-16 US disclosed
US-20060019207-A1 Photothermographic material and image forming method FUJIFILM CORPORATION (JP) 2006-01-26 US disclosed
EP-0722119-B1 Image formation method FUJI PHOTO FILM CO LTD (JP) 2002-04-03 EP disclosed
US-5677104-A HEAT DEVELOPMENT USING A HETEROCYCLIC IMIDE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1997-10-14 US disclosed
EP-0722119-A1 Image formation method FUJI PHOTO FILM CO., LTD. (JP) 1996-07-17 EP disclosed
EP-0060955-B1 SUBSTITUTED URACILS CONTAINING A 2-TETRAHYDROPYRANYL GROUP, PROCESS FOR THEIR PREPARATION AND PESTICIDAL COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1985-05-08 EP disclosed
EP-0060955-A1 Substituted uracils containing a 2-tetrahydropyranyl group, process for their preparation and pesticidal compositions containing them ROUSSEL-UCLAF (FR) 1982-09-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100311175-A1 MASS TAGS FOR QUANTITATIVE ANALYSES SRMS, PTMS, TMT1A POLB 1042/4885MEN1 998/4885KMT2A 1918/4885
US-20110092451-A1 NUCLEOTIDE ANALOGUES WITH QUATERNARY CARBON STEREOGENIC CENTERS AND METHODS OF USE NUDT1, NT5C3B, NTPCR POLB 91/4885MEN1 275/4885KMT2A 1810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.