Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 18/20 | 0.75 |
| ▸ | CAMK1D | Q8IU85 | 2/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | JAK3 | P52333 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18069917 | 1.00 | BTK (0.75) | BTKCAMK1DEGFRJAK3 | |
| SCHEMBL16676700 | 0.87 | BTK (0.57) | BTKEGFRJAK3 | |
| SCHEMBL20998689 | 0.87 | BTK (0.57) | BTKEGFRJAK3 | |
| SCHEMBL18044979 | 0.86 | BTK (0.60) | BTKCAMK1DEGFRJAK3 | |
| SCHEMBL18044980 | 0.86 | BTK (0.60) | BTKCAMK1DEGFRJAK3 | |
| SCHEMBL16676819 | 0.85 | BTK (1.00) | BTKCAMK1D | |
| SCHEMBL18044961 | 0.85 | BTK (1.00) | BTKCAMK1D | |
| SCHEMBL30020786 | 0.85 | CAMK1D (0.73) | BTKCAMK1D | |
| SCHEMBL18068375 | 0.85 | BTK (0.74) | BTKCAMK1D | |
| SCHEMBL30022498 | 0.84 | CAMK1D (0.75) | BTKCAMK1DEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3060550-B1 | HETEROARYL COMPOUNDS AS BTK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2019-05-15 | — | — | EP | disclosed |