Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 2/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11236136 | 0.80 | APOBEC3A (0.61) | APOBEC3AAPOBEC3GALDH1A1LMNAPOLB | |
| SCHEMBL21001088 | 0.72 | — | — | |
| SCHEMBL295784 | 0.67 | APOBEC3A (0.51) | APOBEC3AAPOBEC3GALDH1A1LMNAPOLB | |
| SCHEMBL11238961 | 0.66 | APOBEC3A (0.46) | APOBEC3AAPOBEC3GALDH1A1LMNAPOLB | |
| SCHEMBL14627793 | 0.64 | ALDH1A1 (0.48) | ALDH1A1LMNAALOX15PGR | |
| SCHEMBL6790182 | 0.62 | ALDH1A1 (0.48) | ALDH1A1LMNAPGR | |
| SCHEMBL15129984 | 0.62 | APOBEC3A (0.46) | APOBEC3AAPOBEC3GALDH1A1LMNAPOLB | |
| SCHEMBL20610587 | 0.62 | APOBEC3A (0.42) | APOBEC3AAPOBEC3GALDH1A1LMNAPOLB | |
| SCHEMBL16210192 | 0.61 | APOBEC3A (0.45) | APOBEC3AAPOBEC3GALDH1A1LMNAPOLB | |
| SCHEMBL20825380 | 0.60 | ALDH1A1 (0.43) | ALDH1A1LMNAPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3713609-A2 | SPIRO COMPOUNDS AS MALODOR COUNTERACTING INGREDIENTS | Firmenich SA (CH) | 2020-09-30 | — | — | EP | claimed |
| WO-2019101814-A2 | SPIRO COMPOUNDS AS MALODOR COUNTERACTING INGREDIENTS | FIRMENICH SA (CH) | 2019-05-31 | — | — | WO | claimed |
| EP-3713609-A2 | SPIRO COMPOUNDS AS MALODOR COUNTERACTING INGREDIENTS | Firmenich SA (CH) | 2020-09-30 | — | — | EP | disclosed |
| WO-2019101814-A2 | SPIRO COMPOUNDS AS MALODOR COUNTERACTING INGREDIENTS | FIRMENICH SA (CH) | 2019-05-31 | — | — | WO | disclosed |