Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 3/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | RGS12 | O14924 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL21002149 | 1.00 | GHSR (0.39) | GHSRKMT2AMEN1MMP1ADAM17 | |
| Trifluoroacetic Acid SCHEMBL21002132 | 1.00 | GHSR (0.39) | GHSRKMT2AMEN1MMP1ADAM17 | |
| SCHEMBL21034990 | 0.95 | GHSR (0.43) | GHSRKMT2AMEN1MMP1ADAM17 | |
| SCHEMBL21034987 | 0.95 | GHSR (0.43) | GHSRKMT2AMEN1MMP1ADAM17 | |
| SCHEMBL21036279 | 0.95 | GHSR (0.43) | GHSRKMT2AMEN1MMP1ADAM17 | |
| SCHEMBL21035496 | 0.89 | KMT2A (0.44) | GHSRKMT2AMEN1MMP1ADAM17 | |
| SCHEMBL21034988 | 0.89 | KMT2A (0.44) | GHSRKMT2AMEN1MMP1ADAM17 | |
| SCHEMBL21036263 | 0.89 | KMT2A (0.44) | GHSRKMT2AMEN1MMP1ADAM17 | |
| SCHEMBL21035626 | 0.89 | KMT2A (0.44) | GHSRKMT2AMEN1MMP1ADAM17 | |
| Trifluoroacetic Acid SCHEMBL21001872 | 0.87 | GHSR (0.38) | GHSRKMT2AMEN1MMP1ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |