Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.71 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.71 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.71 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.71 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.63 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.63 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.62 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.62 |
| ▸ | IDO1 | P14902 | 2/20 | 0.60 |
| ▸ | AGXT | P21549 | 2/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29986862 | 1.00 | TAAR1 (0.71) | TAAR1CHRM2CHRM1CHRM3MTNR1A | |
| SCHEMBL21002162 | 0.96 | TAAR1 (0.71) | TAAR1CHRM2CHRM1CHRM3MTNR1A | |
| SCHEMBL21002124 | 0.94 | TAAR1 (0.69) | TAAR1CHRM2CHRM1CHRM3MTNR1A | |
| SCHEMBL30080050 | 0.91 | TAAR1 (0.77) | TAAR1CHRM2CHRM1CHRM3SIGMAR1 | |
| SCHEMBL723511 | 0.91 | TAAR1 (0.77) | TAAR1CHRM2CHRM1CHRM3SIGMAR1 | |
| SCHEMBL145383 | 0.90 | CHRM2 (0.65) | TAAR1CHRM2CHRM1CHRM3MTNR1A | |
| SCHEMBL6953165 | 0.89 | MAOB (0.64) | TAAR1CHRM2CHRM1CHRM3MTNR1A | |
| SCHEMBL11126109 | 0.89 | TAAR1 (0.64) | TAAR1CHRM2CHRM1CHRM3MTNR1A | |
| SCHEMBL11778348 | 0.88 | CHRM2 (0.63) | TAAR1CHRM2CHRM1CHRM3MTNR1A | |
| SCHEMBL11222500 | 0.88 | CHRM2 (0.63) | TAAR1CHRM2CHRM1CHRM3MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200375949-A1 | BISPHENOL COMPOUNDS | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2020-12-03 | — | — | US | disclosed |
| US-20200375949-A1 | BISPHENOL COMPOUNDS | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2020-12-03 | — | — | US | disclosed |
| WO-2019104153-A1 | BISPHENOL COMPOUNDS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2019-05-31 | — | — | WO | disclosed |
| WO-2019104153-A1 | BISPHENOL COMPOUNDS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2019-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200375949-A1 | BISPHENOL COMPOUNDS | RPP30, RPS10, RPS20 | TAAR1 4418/4885CHRM2 4606/4885CHRM1 4068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.