Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.77 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.71 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.71 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.71 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.67 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.67 |
| ▸ | IDO1 | P14902 | 2/20 | 0.64 |
| ▸ | AGXT | P21549 | 2/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.62 |
| ▸ | HTR1A | P08908 | 2/20 | 0.62 |
| ▸ | DRD2 | P14416 | 2/20 | 0.62 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.61 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.61 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.61 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.61 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.61 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.61 |
| ▸ | DAO | P14920 | 1/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL723511 | 1.00 | TAAR1 (0.77) | TAAR1CHRM2CHRM1CHRM3SIGMAR1 | |
| SCHEMBL4060273 | 0.94 | TAAR1 (0.69) | TAAR1CHRM2CHRM1CHRM3SIGMAR1 | |
| SCHEMBL1975466 | 0.94 | TAAR1 (0.69) | TAAR1CHRM2CHRM1CHRM3SIGMAR1 | |
| SCHEMBL4949653 | 0.92 | TAAR1 (0.67) | TAAR1CHRM2CHRM1CHRM3SIGMAR1 | |
| SCHEMBL21002016 | 0.91 | TAAR1 (0.71) | TAAR1CHRM2CHRM1CHRM3SIGMAR1 | |
| SCHEMBL21002162 | 0.91 | TAAR1 (0.71) | TAAR1CHRM2CHRM1CHRM3SIGMAR1 | |
| SCHEMBL29986862 | 0.91 | TAAR1 (0.71) | TAAR1CHRM2CHRM1CHRM3SIGMAR1 | |
| SCHEMBL20078316 | 0.90 | ACHE (0.67) | TAAR1CHRM2CHRM1CHRM3SIGMAR1 | |
| SCHEMBL156300 | 0.89 | TAAR1 (0.69) | TAAR1CHRM2CHRM1CHRM3SIGMAR1 | |
| SCHEMBL21002124 | 0.89 | TAAR1 (0.69) | TAAR1CHRM2CHRM1CHRM3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022236790-A1 | APPLICATION OF EXTRACT OF DENDROBIUM CAPILLIPES RCHB.F., DENDROBIUM LINDLEYI STENDEL AND DENDROBIUM SECUNDUM(BLUME)LINDL. AS α-GLUCOSIDASE INHIBITOR | 中国热带农业科学院热带生物技术研究所 | 2022-11-17 | — | — | WO | claimed |
| WO-2022236790-A1 | APPLICATION OF EXTRACT OF DENDROBIUM CAPILLIPES RCHB.F., DENDROBIUM LINDLEYI STENDEL AND DENDROBIUM SECUNDUM(BLUME)LINDL. AS α-GLUCOSIDASE INHIBITOR | 中国热带农业科学院热带生物技术研究所 | 2022-11-17 | — | — | WO | disclosed |