Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 17/20 | 0.71 |
| ▸ | VEGFA | P15692 | 12/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ARNT | P27540 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21005015 | 0.91 | EPAS1 (0.72) | EPAS1VEGFACYP2C9ARNTCYP2C19 | |
| SCHEMBL18688482 | 0.89 | VEGFA (0.76) | EPAS1VEGFA | |
| SCHEMBL21005016 | 0.89 | VEGFA (0.76) | EPAS1VEGFA | |
| SCHEMBL21005094 | 0.89 | EPAS1 (0.69) | EPAS1VEGFA | |
| SCHEMBL18688469 | 0.85 | VEGFA (0.71) | EPAS1VEGFACYP2C9ARNTCYP2C19 | |
| SCHEMBL21005085 | 0.85 | VEGFA (0.71) | EPAS1VEGFACYP2C9ARNTCYP2C19 | |
| SCHEMBL18054940 | 0.83 | EPAS1 (0.72) | EPAS1VEGFA | |
| SCHEMBL21005434 | 0.83 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL16560985 | 0.83 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL16561000 | 0.83 | EPAS1 (1.00) | EPAS1VEGFACYP2C9ARNTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3417851-B1 | ARYL ETHERS AND USES THEREOF | PELOTON THERAPEUTICS INC (US) | 2020-07-22 | — | — | EP | disclosed |
| EP-3417852-B1 | ARYL ETHERS AND USES THEREOF | PELOTON THERAPEUTICS INC (US) | 2020-02-19 | — | — | EP | disclosed |
| EP-3043784-B9 | ARYL ETHERS AND USES THEREOF | PELOTON THERAPEUTICS INC (US) | 2019-11-20 | — | — | EP | disclosed |
| EP-3043784-B1 | ARYL ETHERS AND USES THEREOF | PELOTON THERAPEUTICS INC (US) | 2019-05-15 | — | — | EP | disclosed |