Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.64 |
| ▸ | KDR | P35968 | 2/20 | 0.64 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | RGS12 | O14924 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.55 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.55 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.55 |
| ▸ | FLT4 | P35916 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL339370 | 0.90 | POLB (0.64) | FGFR1KDRPDGFRAPOLBMEN1 | |
| SCHEMBL17228671 | 0.87 | FGFR1 (0.83) | FGFR1KDRPDGFRAPOLBMEN1 | |
| SCHEMBL14817849 | 0.86 | KMT2A (0.71) | FGFR1KDRPDGFRAPOLBMEN1 | |
| SCHEMBL12463506 | 0.85 | POLB (0.66) | FGFR1KDRPDGFRAPOLBMEN1 | |
| SCHEMBL16070427 | 0.85 | FGFR1 (0.60) | FGFR1KDRPDGFRAPOLBMEN1 | |
| SCHEMBL15587279 | 0.85 | POLB (0.58) | FGFR1KDRPDGFRAPOLBMEN1 | |
| SCHEMBL12463638 | 0.85 | POLB (0.58) | FGFR1KDRPDGFRAPOLBMEN1 | |
| SCHEMBL13964070 | 0.83 | FGFR1 (0.56) | FGFR1KDRPDGFRAPOLBMEN1 | |
| SCHEMBL15810331 | 0.83 | FGFR1 (0.66) | FGFR1KDRPDGFRAPOLBMEN1 | |
| SCHEMBL14392765 | 0.83 | FGFR1 (0.56) | FGFR1KDRPDGFRAPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2677990-B1 | COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING A DIRECT DYE BEARING A DISULFIDE/THIOL FUNCTION, A SPARINGLY OR NON-ETHOXYLATED FATTY ALCOHOL, A CATIONIC SURFACTANT, AN ALKALINE AGENT AND A REDUCING AGENT | OREAL (FR) | 2019-05-15 | — | — | EP | disclosed |