Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.66 |
| ▸ | KDR | P35968 | 2/20 | 0.66 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.64 |
| ▸ | NCOR2 | Q9Y618 | 6/20 | 0.64 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.64 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.64 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | RGS12 | O14924 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17228671 | 0.88 | FGFR1 (0.83) | FGFR1KDRPDGFRAHDAC1HDAC6 | |
| SCHEMBL12463506 | 0.84 | POLB (0.66) | FGFR1KDRPDGFRAHDAC1HDAC6 | |
| SCHEMBL29165263 | 0.84 | FGFR1 (0.80) | FGFR1KDRPDGFRAHDAC1HDAC6 | |
| SCHEMBL21005693 | 0.83 | FGFR1 (0.64) | FGFR1KDRPDGFRAHDAC1HDAC6 | |
| SCHEMBL339370 | 0.83 | POLB (0.64) | FGFR1KDRPDGFRAHDAC1HDAC6 | |
| SCHEMBL16070381 | 0.82 | MEN1 (0.61) | FGFR1KDRPDGFRAHDAC1HDAC6 | |
| SCHEMBL16671948 | 0.81 | HDAC1 (0.60) | FGFR1KDRPDGFRAHDAC1HDAC6 | |
| SCHEMBL15797010 | 0.81 | FGFR1 (0.53) | FGFR1KDRPDGFRAHDAC1HDAC6 | |
| SCHEMBL1505144 | 0.81 | MEN1 (0.70) | FGFR1KDRPDGFRAHDAC1HDAC6 | |
| SCHEMBL1505234 | 0.81 | MEN1 (0.70) | FGFR1KDRPDGFRAHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2931714-B1 | SUBSTITUTED QUINONES OR ANALOGUES AS COLOURING AGENTS | MERCK PATENT GMBH (DE) | 2016-12-21 | — | — | EP | disclosed |
| US-9458142-B2 | Substituted quinones or analogues as colouring agents | MERCK PATENT GMBH (DE) | 2016-10-04 | — | — | US | disclosed |
| US-9458142-B2 | Substituted quinones or analogues as colouring agents | MERCK PATENT GMBH (DE) | 2016-10-04 | — | — | US | disclosed |
| US-20150315177-A1 | SUBSTITUTED QUINONES OR ANALOGUES AS COLOURING AGENTS | MERCK PATENT GMBH (DE) | 2015-11-05 | — | — | US | disclosed |
| US-20150315177-A1 | SUBSTITUTED QUINONES OR ANALOGUES AS COLOURING AGENTS | MERCK PATENT GMBH (DE) | 2015-11-05 | — | — | US | disclosed |
| WO-2014090364-A1 | SUBSTITUTED QUINONES OR ANALOGUES AS COLOURING AGENTS | MERCK PATENT GMBH (DE) | 2014-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150315177-A1 | SUBSTITUTED QUINONES OR ANALOGUES AS COLOURING AGENTS | KRT18, IK, SDHA | FGFR1 2824/4885KDR 4509/4885PDGFRA 3590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.